https://scholars.lib.ntu.edu.tw/handle/123456789/558261
標題: | Value of imprint cytology for ultrasound-guided transthoracic core biopsy | 作者: | WEI-YU LIAO JIH-SHUIN JERNG KUAN-YU CHEN YIH-LEONG CHANG PAN-CHYR YANG Kuo S.-H. |
公開日期: | 2004 | 卷: | 24 | 期: | 6 | 起(迄)頁: | 905-909 | 來源出版物: | European Respiratory Journal | 摘要: | The aim of this study was to investigate the possible additional diagnostic information provided by imprint cytology when performing ultrasound-guided transthoracic core biopsy and to evaluate whether it could optimise the biopsy procedure. A total of 155 transthoracic core biopsies with touch imprint smears were performed under ultrasound guidance, with 127 malignant and 28 benign lesions. The imprint smears were stained using Riu's method and interpreted by a cytopathologist. These were compared with the histopathology of core biopsy specimens and the final diagnosis of malignant versus benign disease. The overall diagnostic accuracy of imprint cytology was 94% (146 out of 155). Histopathological analysis showed an overall accuracy of 94% (146 out of 155), with a sensitivity of 94% (119 out of 127) and negative predictive value of 79% (27 out of 34). The combination of these two methodologies had an increased overall accuracy and negative predictive value of 98% (152 out of 155) and 90% (28 out of 31), respectively. The results of imprint cytology and histopathology were in agreement in 143 patients (92%). In conclusion, imprint cytology of ultrasound-guided transthoracic core biopsy is a sensitive procedure for diagnosing peripheral thoracic lesions, and it may increase the diagnostic accuracy and cancer negative prediction of biopsy alone. With an on-site approach, imprint cytology may help to assess the adequacy of biopsy specimens and optimise the biopsy procedure. ? ERS Journals Ltd 2004. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-10444226545&doi=10.1183%2f09031936.04.00030404&partnerID=40&md5=93b842f9346124f64702a52142b6afe8 https://scholars.lib.ntu.edu.tw/handle/123456789/558261 |
ISSN: | 0903-1936 | DOI: | 10.1183/09031936.04.00030404 | SDG/關鍵字: | adolescent; adult; aged; article; benign tumor; controlled study; cytology; cytopathology; diagnostic accuracy; diagnostic procedure; diagnostic value; echography; female; histopathology; human; major clinical study; male; malignant neoplastic disease; methodology; pathologist; prediction; priority journal; sensitivity and specificity; smear; staining; thorax tumor; transbronchial biopsy; Adolescent; Adult; Aged; Aged, 80 and over; Biopsy, Needle; Chi-Square Distribution; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Thoracic Neoplasms; Ultrasonography, Interventional |
顯示於: | 醫學系 |
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