https://scholars.lib.ntu.edu.tw/handle/123456789/561120
標題: | Clinical significance of nontuberculous mycobacteria isolates in elderly Taiwanese patients | 作者: | Lai C.-C. Tan C.K. Lin S.H. Liu W.L. Liao C.H. YU-TSUNG HUANG PO-REN HSUEH |
公開日期: | 2011 | 卷: | 30 | 期: | 6 | 起(迄)頁: | 779-783 | 來源出版物: | European Journal of Clinical Microbiology and Infectious Diseases | 摘要: | The aim of this study was to investigate the clinical significance of nontuberculous mycobacteria (NTM) isolates in elderly Taiwanese patients. From 2004 through 2008, patients>65 years old with NTM isolation were identified. The definitions of NTM disease followed the American Thoracic Society and Infectious Disease Society of America (ATS/IDSA) criteria. Among the 3,175 NTM isolates, Mycobacterium avium complex (MAC; n=1,118, 35.2%) was the most prevalent species, followed by M. abscessus (n=545, 17.2%). Among the 1,633 elderly patients with NTM isolates, the most prevalent NTM species were MAC (n=592, 36.3%) and M. fortuitum complex (n=311, 19.0%). NTM colonization was found in 1,339 (80.4%) patients and only 326 (19.6%) patients had NTM diseases. During the study period, the annual incidence rates (per 100,000 inpatients and outpatients) of NTM colonization and disease both increased significantly (p<0.0001) from 10.5 to 15.8 and from 2.1 to 4.3, respectively. Isolated pulmonary NTM infections compromised 294 (90.2%) of the 326 elderly cases of NTM disease. In conclusion, this study found an increasing trend in the incidence of both NTM isolates and NTM diseases among elderly Taiwanese patients. MAC and M. abscessus were the most frequent species causing various types of NTM disease. ? 2011 Springer-Verlag. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/561120 | ISSN: | 0934-9723 | DOI: | 10.1007/s10096-011-1155-8 | SDG/關鍵字: | aged; article; bacterial colonization; bacterium isolate; bacterium isolation; controlled study; ethnic group; female; geriatric patient; human; incidence; infection risk; major clinical study; male; mycobacteriosis; Mycobacterium; Mycobacterium abscessus; Mycobacterium avium; Mycobacterium fortuitum; nonhuman; nontuberculous Mycobacterium; prevalence; priority journal; sex difference; Taiwanese; trend study; Aged; Aged, 80 and over; Carrier State; Female; Humans; Incidence; Male; Mycobacterium; Mycobacterium Infections, Atypical; Prevalence; Taiwan |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。