https://scholars.lib.ntu.edu.tw/handle/123456789/561928
標題: | Effects of continuous intravenous epoprostenol therapy on advanced primary pulmonary hypertension in Taiwanese patients | 作者: | HSAO-HSUN HSU JIN-SHING CHEN Kuo S.-H. FU-TIEN CHIANG Ko W.-J. SHUENN-WEN KUO SHU-CHIEN HUANG Lee Y.-C. |
公開日期: | 2005 | 卷: | 104 | 期: | 1 | 起(迄)頁: | 60-63 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Primary pulmonary hypertension (PPH) is a progressive disease for which there is no cure. Continuous intravenous infusion of epoprostenol in selected patients with advanced PPH improves symptoms and survival, but the long-term impact has not been reported in Taiwanese patients. Four patients with advanced PPH treated with epoprostenol therapy were enrolled in this study from July 2000 to September 2001. The basic hemodynamic status, cardiothoracic ratio, 6-minute-walk test results, maximum oxygen consumption, New York Heart Association functional class and survival were re-evaluated before and after 12 months of epoprostenol treatment. One of the patients died after 10 months of epoprostenol therapy due to heart failure, and the other 3 were still alive after a mean of 28 months. The surviving patients had pronounced symptomatic, hemodynamic, functional and survival benefit from epoprostenol therapy. Our results suggest that chronic infusion of epoprostenol can improve functional status and survival of Taiwanese patients with advanced PPH disease. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-14544297973&partnerID=40&md5=f6e05dc5ca96328e9046400435903fe9 https://scholars.lib.ntu.edu.tw/handle/123456789/561928 |
ISSN: | 0929-6646 | SDG/關鍵字: | prostacyclin; antihypertensive agent; prostacyclin; adult; article; case report; clinical feature; drug effect; female; heart failure; hemodynamics; human; male; oxygen consumption; pulmonary hypertension; scoring system; survival rate; treatment outcome; exercise test; intravenous drug administration; pathophysiology; pulmonary hypertension; Adult; Antihypertensive Agents; Epoprostenol; Exercise Test; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Treatment Outcome |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。