https://scholars.lib.ntu.edu.tw/handle/123456789/562574
標題: | High protease activity of Chryseobacterium indologenes isolates associated with invasive infection | 作者: | Pan H.-J. LEE-JENE TENG YEE-CHUN CHEN PO-REN HSUEH PAN-CHYR YANG Ho S.-W. KWEN-TAY LUH |
公開日期: | 2000 | 卷: | 33 | 期: | 4 | 起(迄)頁: | 223-226 | 來源出版物: | Journal of Microbiology, Immunology and Infection | 摘要: | In order to understand virulence factors of Chryseobacterium indologenes isolates associated with invasive infection, enzymatic activities and cellular fatty acid profiles of 42 isolates recovered at National Taiwan University Hospital from January 1994 to December 1996 were studied. Among them, 12 blood isolates were considered as invasive and 30 (recovered from urine, sputa, infected burn wounds, and catheter tips) were noninvasive. All isolates showed strong activities of alkaline phosphatase, acid phosphatase, naphthol-AS-BI-phosphohydrolase, and N-acetyl-β-glucosaminidase, and had no activities for α-galactosidase, β-galactosidase, β-glucuronidase, αmannosidase, and α-fucosidase. The activities of other enzymes were variable. Thirty-two isolates (76%) had varying degrees of protease activity. Two profiles (profiles I and II) of cellular fatty acids of the isolates were found and profile I predominated. There was no significant difference of distribution of cellular fatty acid profiles and activities of enzymes between invasive and noninvasive isolates, except protease activity which was significantly higher in invasive isolates than that in noninvasive isolates. Protease activity may play an important role in virulence on invasive infections caused by C. indologenes. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/562574 | ISSN: | 0253-2662 | SDG/關鍵字: | bacterial enzyme; fatty acid; glucosaminidase; proteinase; virulence factor; article; bacterial virulence; bacterium isolation; burn infection; Chryseobacterium indologenes; disease activity; enzyme activity; enzyme assay; nonhuman; pyomyositis; Taiwan; Endopeptidases; Fatty Acids; Flavobacterium; Gram-Negative Bacterial Infections; Humans; Virulence |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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