https://scholars.lib.ntu.edu.tw/handle/123456789/563798
標題: | Hospital-based allogenic bone bank-10-year experience | 作者: | CHUN-HAN HOU RONG-SEN YANG Hou S.-M. |
公開日期: | 2005 | 卷: | 59 | 期: | 1 | 起(迄)頁: | 41-45 | 來源出版物: | Journal of Hospital Infection | 摘要: | Bone banking in a hospital provides resources of allogenic bone grafts. However, they may transmit infection from donor to recipient. We found few reports discussing the infection rate and monitoring processes associated with bone banks. The discard rate using the screening test was 18.5% (309/1674) in this series. The leading cause was hepatitis B antigen (HBsAg) positive donor serum (67%), followed by Venereal Disease Research Laboratory (VDRL) positive donor serum (15%), and anti-hepatitis C virus (HCV) positive donor serum (12%). The overall infection rate in the recipients was 1.3% (17/1365). Among 1353 implanted allografts, 22 cases (1.6%) had a positive swab culture result after thawing. Only four out of these 22 cases (18.2%) developed infection. However, the wound cultures of the infected recipients were different from the swab culture of thawing allografts except in one case. Among the 1331 recipients with sterile allograft bones, 13 (1%) were found to have infection. In conclusion, our bone bank operates under a strict monitoring system which results in a low infection rate. The recipient's status, the aseptic technique and environment during operation is likely to be more critical in prevention of allograft-related infection. ? 2004 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-10244219994&doi=10.1016%2fj.jhin.2004.03.017&partnerID=40&md5=e23050dc8dad3d5a188e7272c0fb010b https://scholars.lib.ntu.edu.tw/handle/123456789/563798 |
ISSN: | 0195-6701 | DOI: | 10.1016/j.jhin.2004.03.017 | SDG/關鍵字: | cephalosporin; hepatitis B antigen; hepatitis C antibody; meticillin; adolescent; adult; aged; antibiotic prophylaxis; article; asepsis; bacterium culture; bone allograft; bone disease; bone infection; bone transplantation; controlled study; disease transmission; donor; female; graft infection; health care facility; hospital infection; human; infection control; infection prevention; infection rate; intraoperative period; major clinical study; male; recipient; school child; screening test; serodiagnosis; surgical infection; thawing; venereal disease reaction test; Adolescent; Adult; Aged; Asepsis; Bone Banks; Bone Transplantation; Child; Cross Infection; Female; Guideline Adherence; Hospital Departments; Hospitals, University; Humans; Infection Control; Male; Mass Screening; Middle Aged; Orthopedics; Practice Guidelines; Program Evaluation; Quality Assurance, Health Care; Retrospective Studies; Taiwan; Transplantation, Homologous |
顯示於: | 醫學系 |
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