https://scholars.lib.ntu.edu.tw/handle/123456789/566631
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Yang C.-Y. | en_US |
dc.contributor.author | CHUN-YI LU | en_US |
dc.contributor.author | CHIN-YUN LEE | en_US |
dc.contributor.author | PEI-LAN SHAO | en_US |
dc.contributor.author | Wang C.-Y. | en_US |
dc.contributor.author | Wu T.-Z. | en_US |
dc.contributor.author | LI-MIN HUANG | en_US |
dc.date.accessioned | 2021-06-24T07:19:45Z | - |
dc.date.available | 2021-06-24T07:19:45Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1684-1182 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-4644226377&partnerID=40&md5=6be7efd06f5d5f347e332872acd96dd4 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/566631 | - |
dc.description.abstract | The safety, tolerability and immunogenicity of inactivated hepatitis A vaccine (VAQTA, Merck and Co. Inc., West Point, PA, USA) were investigated in 28 seronegative healthy adult volunteers. The age range was 25-35 years, and the mean age was 29 years. Two doses of the vaccine, each containing 50 U of hepatitis A virus antigen, were administered into the deltoid region 24 weeks apart. No serious vaccine-related adverse reactions were reported. Four weeks after the first dose, the geometric mean titer (GMT) was 150 mlU/mL, and the seroconversion rate was 100%. Twenty eight weeks after the first dose (4 weeks following the second dose), the GMT was 4576 mIU/mL. This study demonstrated that VAQTA is safe and highly immunogenic in healthy young adults in Taiwan. | en_US |
dc.relation.ispartof | Journal of Microbiology, Immunology and Infection | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | hepatitis A antigen; hepatitis A vaccine; inactivated vaccine; adult; antibody blood level; antibody titer; article; drug dose regimen; drug efficacy; drug safety; drug screening; drug tolerability; erythema; fatigue; female; hepatitis A; Hepatitis A virus; human; human experiment; immunogenicity; injection pain; male; normal human; open study; seroconversion; Taiwan; Adult; Antibodies, Viral; Drug Tolerance; Female; Hepatitis A Vaccines; Hepatitis A virus; Humans; Male; Safety; Time Factors; Vaccines, Inactivated | - |
dc.title | An open study of inactivated hepatitis A vaccine (VAQTA) in Taiwanese healthy adult volunteers: Safety, tolerability, and immunogenicity | en_US |
dc.type | journal article | en |
dc.identifier.pmid | 15340648 | - |
dc.identifier.scopus | 2-s2.0-4644226377 | - |
dc.relation.pages | 216-218 | en_US |
dc.relation.journalvolume | 37 | en_US |
dc.relation.journalissue | 4 | en_US |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Pediatrics-NTUHHC | - |
crisitem.author.dept | Laboratory Medicine-NTUHHC | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | National Taiwan University Children's Hospital | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.orcid | 0000-0002-5240-2808 | - |
crisitem.author.orcid | 0000-0002-3938-377X | - |
crisitem.author.orcid | 0000-0003-3334-1330 | - |
crisitem.author.orcid | 0000-0002-9291-260X | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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