https://scholars.lib.ntu.edu.tw/handle/123456789/566667
標題: | Hepatitis a virus infection in Taipei in 1999 | 作者: | Tseng H.-Y. CHUN-YI LU CHIN-YUN LEE Yeh C.-C. Lin S.-C. Shih W.-Y. Wu S.-Y. MEI-HWEI CHANG LI-MIN HUANG |
公開日期: | 2001 | 卷: | 100 | 期: | 9 | 起(迄)頁: | 604-607 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background and purpose: Hepatitis A is a disease that is heavily affected by sanitation status. Hepatitis A is much less prevalent compared with decades ago in Taiwan, as in many rapidly developing regions. Hepatitis A vaccine is still self-paid under the National Health Insurance program and is still not widely utilized by the general public in Taiwan. This seroepidemiologic study evaluated the prevalence of anti-hepatitis A virus (anti-HAV) seropositivity in Taipei in 1999. Methods: A total of 1017 serum samples from healthy inhabitants in Taipei were examined for anti-HAV antibody by qualitative enzyme immunoassay. Results: The overall seroprevalence rate was 25.2% (255/1013) in the nonvaccinated population. The seropositivity rate for anti-HAV antibody among children younger than 12 months old was 23.3%. The rates dropped to between 1% and 4.8% among subjects between 1 and 20 years of age. A markedly higher rate of 40% was observed in subjects aged between 20 and 30 years. The seropositivity rate in subjects aged 31 to 50 was 80%. More than 90% of subjects older than 50 years were seropositive. The vaccination rate was low (0.5%). Conclusion: Our findings indicate that Taipei is an area of intermediate endemicity for hepatitis A virus. To achieve better herd immunity, a more active approach to the adoption of hepatitis A vaccine is warranted. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034750026&partnerID=40&md5=7d16d11c38db318b679a64754110be2c https://scholars.lib.ntu.edu.tw/handle/123456789/566667 |
ISSN: | 0929-6646 | SDG/關鍵字: | hepatitis A vaccine; virus antibody; adult; age; antibody detection; article; blood sampling; child; controlled study; endemic disease; enzyme immunoassay; female; hepatitis A; human; human experiment; infant; male; normal human; seroepidemiology; seroprevalence; Taiwan; vaccination; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Hepatitis A; Hepatitis A Vaccines; Humans; Infant; Infant, Newborn; Male; Middle Aged; Seroepidemiologic Studies; Taiwan; Time Factors; Travel; Vaccination |
顯示於: | 醫學系 |
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