https://scholars.lib.ntu.edu.tw/handle/123456789/568846
DC Field | Value | Language |
---|---|---|
dc.contributor.author | JIA-HORNG KAO | en_US |
dc.contributor.author | CHUN-JEN LIU | en_US |
dc.contributor.author | PEI-JER CHEN | en_US |
dc.contributor.author | Chen W. | en_US |
dc.contributor.author | Hsiang S.-C. | en_US |
dc.contributor.author | Lai M.-Y. | en_US |
dc.contributor.author | DING-SHINN CHEN | en_US |
dc.date.accessioned | 2021-07-03T03:36:06Z | - |
dc.date.available | 2021-07-03T03:36:06Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 0146-6615 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984537091&doi=10.1002%2f%28SICI%291096-9071%28199712%2953%3a4%3c348%3a%3aAID-JMV6%3e3.0.CO%3b2-7&partnerID=40&md5=cdb8f2bd29f4e6e68bb8b7a43a6bd446 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/568846 | - |
dc.description.abstract | Although infection with GB virus-C/hepatitis G virus (GBV-C/HGV) by blood transfusion is well documented, little is known about the other routes of transmission. The prevalence of GBV-C/HGV infection in spouses of index patients and the related risk factors were studied. Hepatitis C virus (HCV) and GBV-C/HGV infections were studied in spouses of 100 patients with hepatitis C, of whom 12 were found to be also positive for GBV-C/HGV RNA. For couples both with GBV-C/HGV viremia, nucleotide sequences of the divergent envelope region were analyzed by phylogenetic tree constructions. For HCV infection, anti-HCV was found in 14 (14%) of the 100 spouses. Five spouses (42%) of the 12 patients with dual infection of GBV-C/HGV and HCV had evidence of GBV-C/HGV infection, three had viral RNA, and two had antibodies to a recombinant HGV envelope protein E2. Nucleotide sequence comparison and phylogenetic tree analysis of the genome in the GBV-C/HGV infected couple revealed the isolates to be closely related. These results suggest that spouses of patients with GBV-C/HGV infection are at a higher risk of acquiring GBV-C/HGV as compared with HCV, and they should be educated to avoid GBV-C/HGV infection from their spouses, in case GBV-C/HGV is shown to be pathogenic. | en_US |
dc.publisher | John Wiley and Sons Inc. | en_US |
dc.relation.ispartof | Journal of Medical Virology | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | adult; aged; article; blood transfusion; female; Hepatitis C virus; Hepatitis G virus; human; major clinical study; male; phylogeny; risk factor; spouse; virus gene; virus isolation; virus transmission; GB virus C/Hepatitis G virus; Hepatitis C virus | - |
dc.title | Interspousal transmission of GB virus-C/Hepatitis G virus: A comparison with hepatitis C virus | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1002/(SICI)1096-9071(199712)53:4<348 | - |
dc.identifier.pmid | 9407382 | - |
dc.identifier.scopus | 2-s2.0-84984537091 | - |
dc.relation.pages | 348-353 | en_US |
dc.relation.journalvolume | 53 | en_US |
dc.relation.journalissue | 4 | en_US |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-2442-7952 | - |
crisitem.author.orcid | 0000-0002-6202-0993 | - |
crisitem.author.orcid | 0000-0001-8316-3785 | - |
crisitem.author.orcid | 0000-0001-7791-6154 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
Appears in Collections: | 臨床醫學研究所 |
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