https://scholars.lib.ntu.edu.tw/handle/123456789/570015
標題: | Effects of fluoride and epigallocatechin gallate on soft-drink-induced dental erosion of enamel and root dentin | 作者: | YIN-LIN WANG HAO-HUENG CHANG YU-CHIH CHIANG Lu Y.-C. CHUN-PIN LIN |
公開日期: | 2018 | 出版社: | Elsevier B.V. | 卷: | 117 | 期: | 4 | 起(迄)頁: | 276-282 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/Purpose: Fluoride and epigallocatechin gallate (EGCG) have been proven to prevent dental caries. The purpose of this study was to evaluate the effects of fluoride and EGCG on soft-drink-induced dental erosion in vitro. Methods: Forty enamel and dentin specimens were prepared from extracted human teeth. The specimens were divided into 4 groups and treated separately with distilled water (as control), 0.5 M sodium fluoride (NF), 400 μM EGCG (EG), and a solution containing 0.5 M NaF and 400 μM EGCG (FG). Cyclic erosive treatment was performed according to the experimental procedures. The specimens were analyzed using laser scanning confocal microscopy, scanning electron microscopy, and a microhardness tester. The data were analyzed using ANOVA and Bonferroni's post hoc test. The significance level was set at 5%. Results: The amount of substance loss was lower in the NF and EG groups than in the control group (p < 0.05). The erosion-caused substance loss was more pronounced in the dentin than in the enamel specimens. Surface microhardness loss was lower in the NF and EG groups than in the control group (p < 0.05). The diameter of the dentinal tubule was wider in the control group than in the NF and EG groups (p < 0.05). No combined effects were observed in the FG group. Conclusion: Both fluoride and EGCG are effective in preventing soft-drink-induced erosion compared with the control group. Fluoride and EGCG may interfere with each other. The mechanisms of the anti-erosive effect need to be explored in the future. ? 2018 |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043993689&doi=10.1016%2fj.jfma.2018.01.020&partnerID=40&md5=514f01feb7aad7fd4afba02d4efccc2d https://scholars.lib.ntu.edu.tw/handle/123456789/570015 |
ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2018.01.020 | SDG/關鍵字: | distilled water; epigallocatechin gallate; fluoride; catechin; epigallocatechin gallate; sodium fluoride; Article; caries prevention; confocal laser scanning microscopy; controlled study; dentin; enamel; hardness; human; in vitro study; scanning electron microscopy; soft drink; tooth disease; analogs and derivatives; carbonated beverage; dentin; enamel; tooth disease; tooth root; Carbonated Beverages; Catechin; Dental Enamel; Dentin; Humans; Microscopy, Electron, Scanning; Sodium Fluoride; Tooth Erosion; Tooth Root |
顯示於: | 臨床牙醫學研究所 |
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