https://scholars.lib.ntu.edu.tw/handle/123456789/570608
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHIH-HUNG WANG | en_US |
dc.contributor.author | CHENG-YI WU | en_US |
dc.contributor.author | MENG-CHE WU | en_US |
dc.contributor.author | WEI-TIEN CHANG | en_US |
dc.contributor.author | CHIEN-HUA HUANG | en_US |
dc.contributor.author | MIN-SHAN TSAI | en_US |
dc.contributor.author | TSUNG-CHIEN LU | en_US |
dc.contributor.author | Chou, Eric | en_US |
dc.contributor.author | Hsieh, Yu-Lin | en_US |
dc.contributor.author | WEN-JONE CHEN | en_US |
dc.date.accessioned | 2021-07-08T01:07:36Z | - |
dc.date.available | 2021-07-08T01:07:36Z | - |
dc.date.issued | 2021-06-11 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/570608 | - |
dc.description.abstract | To investigate whether the effects of sodium bicarbonate (SB) during cardiopulmonary resuscitation (CPR) would be influenced by blood pH and administration timing. Adult patients experiencing in-hospital cardiac arrest (IHCA) from 2006 to 2015 were retrospectively screened. Early intra-arrest blood gas data were obtained within 10 min of CPR. Multivariable logistic regression analysis and generalised additive models were used for effect estimation and data exploration, respectively. A total of 1060 patients were included. Only 59 patients demonstrated favourable neurological status at hospital discharge. Blood pH ≤ 7.18 was inversely associated with favourable neurological outcome (odds ratio [OR], 0.24; 95% confidence interval [CI], 0.11-0.52; p value < 0.001) while SB use was not. In the interaction analysis for favourable neurological outcome, significant interactions were noted between SB use and time to SB (SB use × time to SB ≥ 20 min; OR 6.16; 95% CI 1.42-26.75; p value = 0.02). In the interaction analysis for survival to hospital discharge, significant interactions were noted between SB use and blood pH (Non-SB use × blood pH > 7.18; OR 1.56; 95% CI 1.01-2.41; p value = 0.05). SB should not be empirically administered for patients with IHCA since its effects may be influenced by blood pH and administration timing. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Scientific reports | en_US |
dc.title | A retrospective study on the therapeutic effects of sodium bicarbonate for adult in-hospital cardiac arrest | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1038/s41598-021-91936-3 | - |
dc.identifier.pmid | 34117316 | - |
dc.identifier.scopus | 2-s2.0-85107787216 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85107787216 | - |
dc.relation.journalvolume | 11 | en_US |
dc.relation.journalissue | 1 | en_US |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.orcid | 0000-0003-0802-7825 | - |
crisitem.author.orcid | 0000-0002-1966-0469 | - |
crisitem.author.orcid | 0000-0002-9584-3486 | - |
crisitem.author.orcid | 0000-0002-1880-7932 | - |
crisitem.author.orcid | 0000-0003-2981-4537 | - |
crisitem.author.orcid | 0000-0002-2862-7572 | - |
crisitem.author.orcid | 0000-0003-2729-7142 | - |
crisitem.author.orcid | 0000-0002-2098-5922 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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