|Title:||The postnatal risk, resuscitation success rate and outcomes of pediatric sudden death in Taiwan||Authors:||Liu, Hsin Ming
Chiu, Sheunn Nan
Chen, Hui Chi
Kao, Feng Yu
Huang, San Kuei
|Keywords:||Adolescent | Children | Infant | Potentially sudden death event | Rescued sudden death;Adolescent; Children; Infant; Potentially sudden death event; Rescued sudden death||Issue Date:||1-Jan-2021||Journal Volume:||37||Journal Issue:||3||Source:||Acta Cardiologica Sinica||Abstract:||
Background: The epidemiology of pediatric potentially sudden death (SD) events and the rescue rate remain unclear. Methods:We established a birth cohort (2000-2014) from a national database 2000-2015. Results: Of 3,097,277 live births, we identified 3126 children (56.1% male) with potentially SD events, including 887 who were rescued. The cumulative risk of potentially SD events for each neonate was 0.30, 0.62, 0.91, 1.05, and 1.13 per 1000 by 2 months, 0, 5, 11 and 14 years of age, respectively. Overall, 28.3% of the children were rescued from SD events, with a higher rate in neonates (69.6%) but lower rate in postneonatal infants. A cardiac diagnosis was noted in 596 (19.1%) patients, including congenital heart disease (CHD) (388), cardiac arrest (151), cardiomyopathy (23), myocarditis (12), Kawasaki disease (7) and arrhythmia (36). Coexisting severe CHD and events in postneonatal infancy were associated with a lower chance of resuscitation, whereas events within 1 week of age had a higher chance of resuscitation. Anoxic brain damage was noted in 174 (19.7%) patients and late death occurred in 348 (39.3%) patients after being rescued from SD. Late death was more common in males, those with anoxic brain damage, those with coexisting severe CHD, and postneonatal infants. Conclusions: In this birth cohort study, the postnatal cumulative risk of potentially SD events was 1 in 885 newborns by 14 years of age. Postneonatal infants and those with coexisting severe CHD had the highest risk and worst outcomes.
|URI:||https://scholars.lib.ntu.edu.tw/handle/123456789/571127||ISSN:||10116842||DOI:||10.6515/ACS.202105_37(3).20201019C||metadata.dc.subject.other:||adolescent; Article; cardiomyopathy; cardiovascular risk; child; congenital heart disease; female; heart arrest; human; infant; live birth; major clinical study; male; mortality rate; myocarditis; newborn; newborn death; outcome assessment; perinatal morb
|Appears in Collections:||醫學院附設醫院 (臺大醫院)|
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