https://scholars.lib.ntu.edu.tw/handle/123456789/571484
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lin M.-C. | en_US |
dc.contributor.author | Wang K.-C. | en_US |
dc.contributor.author | SHOEI-SHENG LEE | en_US |
dc.date.accessioned | 2021-07-16T06:18:28Z | - |
dc.date.available | 2021-07-16T06:18:28Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 94536 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0242723003&doi=10.1002%2fjccs.200100021&partnerID=40&md5=d695ce37399db2a63ef267fff71b8d3b | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/571484 | - |
dc.description.abstract | Fractions major in ginsenosides Rg1 and Rb1 from Sanchi saponins were transformed by human fecal flora. This study yielded the corresponding aglycone, protopanaxatriol, in 49.4% from Rg1, protopanaxadiol 20-O-glucoside in 54.8% from Rb1, and dihydroprotopanaxadiol 20-O-glucoside in 87.6% from dihydro Rb1, by incubation with healthy feces for 70 h in subgram level. Nevertheless large-scale incubation of crude Sanchi saponins revealed the complete biotransformation of Rb1 and the almost unchanged Rg1. A small amount of Rg1 was found to be converted into 20R-ginsenoside Rh1 and its dehydration product, 20(22)Z-ginsenoside Rh4. | - |
dc.relation.ispartof | Journal of the Chinese Chemical Society | - |
dc.subject | 20(22)Z-Ginsenoside Rh4; 20R-ginsenoside Rh1; Human microflora; Microbial transformation; Sanchi saponins | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | Transformation of ginsenosides Rg1 and Rb1, and crude Sanchi saponins by human intestinal microflora | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1002/jccs.200100021 | - |
dc.identifier.scopus | 2-s2.0-0242723003 | - |
dc.relation.pages | 113-120 | - |
dc.relation.journalvolume | 48 | - |
dc.relation.journalissue | 1 | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Pharmacy | - |
crisitem.author.orcid | 0000-0002-6628-2448 | - |
crisitem.author.parentorg | College of Medicine | - |
Appears in Collections: | 藥學系 |
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