https://scholars.lib.ntu.edu.tw/handle/123456789/572058
標題: | Idiopathic multicentric osteolysis with nephropathy | 作者: | Chiang H.-W. TZONG-SHINN CHU Tsai C.-C. Hsieh B.-S. |
關鍵字: | Glomerulosclerosis; Idiopathic multicentric osteolysis; Nephropathy | 公開日期: | 2000 | 卷: | 99 | 期: | 3 | 起(迄)頁: | 243-247 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Idiopathic multicentric osteolysis is a rare syndrome that manifests with progressive loss of carpal and tarsal bones in childhood. Affected children have arthritic-like episodes, followed by progressive deformities, radiographic osteolytic changes, and variable degrees of disability. A rare form of this disease (type III, sporadic) is associated with serious nephropathy. We present the first reported case of type III idiopathic multicentric osteolysis in a Chinese woman. The patient, a 34-year-old woman with normal mental development and no family history of bone or kidney disease, presented with a 4-day history of nausea and vomiting. She had shortening anti swelling of the hands, which had occurred in childhood and persisted at the time of admission. X-ray studies showed disappearance of the carpal bones, and multiple osseous erosions of the tarsal bones. Hypertension, severe azotemia, and metabolic acidosis were also noted. Advanced renal disease was documented after a series of investigations, including renal biopsy. She is now dialysis-dependent. This case illustrates the importance of early diagnosis and management of idiopathic multicentric osteolysis with nephropathy. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034022867&partnerID=40&md5=f05dad64e0378b049fa9b7ba5f6ec5ab https://scholars.lib.ntu.edu.tw/handle/123456789/572058 |
ISSN: | 0929-6646 | SDG/關鍵字: | adult; article; bone malformation; carpal bone; case report; childhood disease; clinical feature; dialysis; disease classification; early diagnosis; female; human; idiopathic disease; kidney disease; osteolysis; tarsal bone; Adult; Female; Humans; Kidney Diseases; Osteolysis, Essential |
顯示於: | 醫學教育暨生醫倫理學科所 |
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