https://scholars.lib.ntu.edu.tw/handle/123456789/572924
標題: | Laparoscopic Sleeve Gastrectomy for Type 2 Diabetes Mellitus: Long-Term Result and Recurrence of Diabetes | 作者: | Lee M.-H Almalki O.M Lee W.-J Chen S.-C JEN-CHIH CHEN Wu C.-C. |
關鍵字: | C peptide; hemoglobin A1c; insulin; ABCD2 score; adult; age; aged; Article; body mass; body weight loss; clinical outcome; disease duration; female; follow up; hemoglobin blood level; human; insulin resistance; laparoscopic sleeve gastrectomy; major clinical study; male; non insulin dependent diabetes mellitus; obese patient; obesity; priority journal; recurrent disease; remission; retrospective study; gastrectomy; laparoscopy; morbid obesity; treatment outcome; Body Mass Index; Diabetes Mellitus, Type 2; Female; Gastrectomy; Humans; Laparoscopy; Male; Obesity, Morbid; Retrospective Studies; Treatment Outcome | 公開日期: | 2020 | 卷: | 30 | 期: | 10 | 起(迄)頁: | 3669-3674 | 來源出版物: | Obesity Surgery | 摘要: | Background: Laparoscopic sleeve gastrectomy (LSG) is becoming a primary bariatric/metabolic surgical procedure for treating obesity and related type 2 diabetes mellitus (T2D). This study presents the long-term outcome of LSG about the remission and recurrence of T2D. Methods: A total of 59 obese patients (38 women and 21 male) with T2D (mean body mass index [BMI] 37.6 ± 5.1?kg/m2) who underwent LSG from 2006 to 2014 with complete 5?years followed up were selected for present study. The remission of T2D was evaluated in stratified groups using the ABCD scoring system which is composed of the age, BMI, C-peptide, and duration of T2D. Results: The weight loss at 5?years after surgery was 23.5% and the mean BMI decreased to 27.7 ± 4.5?kg/m2. The mean HbA1c decreased from 8.1 to 6.1% at 5?years. The 1-year and 5-year complete remission rate (HbA1c < 6.0%) was 62.7% and 42.4%. Thirteen patients (35.1%) out of 37 patients who had their T2D remission at 1?year had their T2D recurrent at 5?years. Patients with ABCD score higher than 5 had a higher long-term T2D remission rate and less recurrence of their T2D than those with ABCD score less than 5. The remission and recurrence of T2D after were associated with a weight loss more than 20%. Conclusion: LSG is an effective procedure for T2D treatment but a significant portion of patients had their T2D recurrence at long-term. LSG is better recommended to patients with their ABCD score ? 5 and dedication to maintain a good weight loss is important. ? 2020, Springer Science+Business Media, LLC, part of Springer Nature. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085479685&doi=10.1007%2fs11695-020-04737-4&partnerID=40&md5=7c3f478c0af566baf3c458d5aa4e22dc https://scholars.lib.ntu.edu.tw/handle/123456789/572924 |
ISSN: | 9608923 | DOI: | 10.1007/s11695-020-04737-4 |
顯示於: | 生物科技研究所 |
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