https://scholars.lib.ntu.edu.tw/handle/123456789/575606
標題: | Laparoendoscopic single-site nephroureterectomy for upper urinary tract urothelial carcinoma: Outcomes of an international multi-institutional study of 101 patients | 作者: | Park S.Y. Rha K.H. Autorino R. Derweesh I. Liastikos E. Tsai Y.C. Seo I.Y. Nagele U. Abdel-Karim A.M. Herrmann T. Han D.H. Rais-Bahrami S. Lee S.W. Kim K.S. Fornara P. Kallidonis P. Springer C. ?lsalmy S. SHIH-CHIEH CHUEH Ho C.-H. Panumatrassamee K. Kopp R. Stolzenburg J.-U. Richstone L. Chung J.H. Shin T.Y. Greco F. Kaouk J.H. |
關鍵字: | laparoendoscopic single-site surgery; LESS; multi-institutional; transitional cell carcinoma | 公開日期: | 2013 | 卷: | 112 | 期: | 5 | 起(迄)頁: | 610-615 | 來源出版物: | BJU International | 摘要: | Objective To report a large multi-institutional series of laparoendoscopic single-site (LESS) nephroureterectomy (NU). Materials and Methods Data on all cases of LESS-NU performed between 2008 and 2012 at 15 institutions were retrospectively gathered. The main demographic data and perioperative outcomes were analysed. Results The study included 101 patients whose mean (sd) age was 66.4 (9.9) years and mean (sd) body mass index was 24.8 (4) kg/m2, and of whom 29.7% had undergone previous abdominal/pelvic surgery. The mean (sd) operating time was 221.4 (73.7) min, estimated blood loss 231.7 (348.0) mL. A robot-assisted LESS technique was applied in 25.7% of cases. An extra trocar was inserted in 28.7% of cases to complete the procedure. Conversion to open surgery was necessary in three cases (3.0%). There was no bladder cuff excision in 20.8% of cases, and excision was carried out using a variety of techniques in the remaining cases. Six intra-operative complications occurred (5.9%). The mean (sd) length of hospital stay was 6.3 (3.5) days. The overall postoperative complication rate was 10.0%, and most of the complications were low grade (Clavien grades 1 and 2). The mean tumour size was 3.1 (1.9) cm. Pathological staging was pTis in two patients, pTa in 12 patients, pT1 in 42 patients, pT2 in 20 patients, pT3 in 23 patients and pT4 in two patients. Pathological grade was high in 71 and low in 30 patients. At a mean follow-up of 14 months, six patients (5.9%) had died. Disease recurrence (including distant and bladder recurrence) was detected in 22.8% of patients, with a mean time to recurrence of 11.5 months. Conclusions This study reports the largest multi-institutional experience of LESS-NU to date. Peri-operative outcomes mirror those of published standard laparoscopy series. Despite encouraging early findings, longer follow-up is needed to determine the oncological efficacy of the procedure. ? 2013 BJU International. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84882243957&doi=10.1111%2fj.1464-410X.2012.11775.x&partnerID=40&md5=d70fff373d6b5715fab7b1e5fbb7235e https://scholars.lib.ntu.edu.tw/handle/123456789/575606 |
ISSN: | 1464-4096 | DOI: | 10.1111/j.1464-410X.2012.11775.x | SDG/關鍵字: | abdominal abscess; abdominal surgery; acute kidney failure; adult; anemia; article; bladder cuff excision; bladder metastasis; bladder surgery; body mass; cancer staging; conversion to open surgery; distant metastasis; female; fever; follow up; human; ileus; laparoendoscopic single site surgery; length of stay; major clinical study; male; nephroureterectomy; operation duration; operative blood loss; pelvis surgery; peroperative complication; postoperative complication; priority journal; robotics; transitional cell carcinoma; trocar; tumor volume; wound infection; laparoendoscopic single-site surgery; LESS; multi-institutional; transitional cell carcinoma; Aged; Body Mass Index; Carcinoma, Transitional Cell; Female; Follow-Up Studies; Humans; Intraoperative Complications; Kidney Neoplasms; Laparoscopy; Length of Stay; Male; Nephrectomy; Retrospective Studies; Robotics; Survival Analysis; Treatment Outcome; Ureteral Neoplasms |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。