https://scholars.lib.ntu.edu.tw/handle/123456789/577127
標題: | Substitutes and colloidal system for vitreous replacement and drug delivery: Recent progress and future prospective | 作者: | Thacker M Tseng C.-L Lin F.-H. Lin, Feng-Huei |
關鍵字: | Eye protection; Silicones; Sols; Diabetic retinopathy; Pathological conditions; Polymeric hydrogels; Recent researches; Retinal detachments; Short-term solutions; Vitreoretinal surgery; Vitreous substitute; Drug delivery | 公開日期: | 2021 | 卷: | 13 | 期: | 1 | 起(迄)頁: | 1-15 | 來源出版物: | Polymers | 摘要: | Vitreoretinal surgeries for ocular diseases such as complicated retinal detachment, diabetic retinopathy, macular holes and ocular trauma has led to the development of various tamponades over the years in search for an ideal vitreous substitute. Current clinically used tamponade agents such as air, perfluorocarbons, silicone oil and expansile gases serve only as a short-term solution and harbors various disadvantages. However, an ideal long-term substitute is yet to be discovered and recent research emphasizes on the potential of polymeric hydrogels as an ideal vitreous substitute. This review highlights the recent progress in the field of vitreous substitution. Suitability and adverse effects of various tamponade agents in present day clinical use and biomaterials in the experimental phase have been outlined and discussed. In addition, we introduced the anatomy and functions of the native vitreous body and the pathological conditions which require vitreous replacement. ? 2020 by the authors. Licensee MDPI, Basel, Switzerland. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098863675&doi=10.3390%2fpolym13010121&partnerID=40&md5=024936ff3ae04ebd6f88e86a68a5dc89 https://scholars.lib.ntu.edu.tw/handle/123456789/577127 |
ISSN: | 20734360 | DOI: | 10.3390/polym13010121 | SDG/關鍵字: | Eye protection; Silicones; Sols; Diabetic retinopathy; Pathological conditions; Polymeric hydrogels; Recent researches; Retinal detachments; Short-term solutions; Vitreoretinal surgery; Vitreous substitute; Drug delivery |
顯示於: | 醫學工程學研究所 |
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