https://scholars.lib.ntu.edu.tw/handle/123456789/578168
標題: | Estimating error models for whole genome sequencing using mixtures of Dirichlet-multinomial distributions | 作者: | STEVEN HUNG-HSI WU Schwartz, R.S Winter, D.J Conrad, D.F Cartwright, R.A. |
公開日期: | 2017 | 出版社: | Oxford University Press | 卷: | 33 | 期: | 15 | 來源出版物: | Bioinformatics | 摘要: | Accurate identification of genotypes is an essential part of the analysis of genomic data, including in identification of sequence polymorphisms, linking mutations with disease and determining mutation rates. Biological and technical processes that adversely affect genotyping include copy-number-variation, paralogous sequences, library preparation, sequencing error and reference-mapping biases, among others. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/578168 | ISSN: | 1367-4803 1460-2059 |
DOI: | 10.1093/bioinformatics/btx133 |
顯示於: | 農藝學系 |
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Estimating error models for whole genome sequencing using mixtures of Dirichlet-multinomial distributions | 510.13 kB | Adobe PDF | 檢視/開啟 |
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