https://scholars.lib.ntu.edu.tw/handle/123456789/578389
標題: | Anti-neutrophil cytoplasmic autoantibody-associated vasculitides | 作者: | Lee S.-Y. Wang H.-P. Chen T.-H. Hung P.-H. KUAN-YU HUNG |
公開日期: | 2020 | 出版社: | Society of Internal Medicine of Taiwan | 卷: | 31 | 期: | 2 | 起(迄)頁: | 91-105 | 來源出版物: | Journal of Internal Medicine of Taiwan | 摘要: | Although antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) rarity and still unknown causes, research on those vasculitides has been very active over the past few decades. AAV are small-vessel vasculitides and the clinical symptoms vary and affect several organs, such as the kidney and lung. AAV is similar to other autoimmune diseases and develops in patients with a predisposing genetic background who have been exposed to causative environmental factors. AAV pathogenic mechanisms should explain the pathologic and clinical manifestations of AAV, which involves ANCA-mediated neutrophil overactivations that subsequently release inflammatory cytokines. AAV clinical diagnosis and treatment should avoid delay to prevent end organ damage, particularly renal disease. Adverse responses to treatment AAV are common, as are relapses, so requiring long term follow-up is needed. ? 2020 Society of Internal Medicine of Taiwan. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091442626&doi=10.6314%2fJIMT.202004_31%282%29.04&partnerID=40&md5=13708e04a30f50f873ac89c2609c1cff https://scholars.lib.ntu.edu.tw/handle/123456789/578389 |
ISSN: | 1016-7390 | DOI: | 10.6314/JIMT.202004_31(2).04 | SDG/關鍵字: | cytokine; neutrophil cytoplasmic antibody; ANCA associated vasculitis; Article; cytokine release; human; kidney disease |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。