https://scholars.lib.ntu.edu.tw/handle/123456789/578776
標題: | Acute kidney injury in the elderly: Only the tip of the iceberg | 作者: | CHIA-TER CHAO Tsai H.-B. YU-FENG LIN Ko W.-J. |
公開日期: | 2014 | 出版社: | Elsevier | 卷: | 5 | 期: | 1 | 起(迄)頁: | 7-12 | 來源出版物: | Journal of Clinical Gerontology and Geriatrics | 摘要: | The incidence of acute kidney injury (AKI) is rising in individuals of all ages; however, elderly patients (older than 65 years) are particularly susceptible to the development of AKI due to the structural and functional deterioration of the kidneys associated with the aging process, a decreased renal reserve, the presence of comorbidities, and the reduced ability to recover. Older patients with AKI carry an elevated risk of both short-term and long-term mortality, and survivors are often left with chronic kidney disease (CKD) that eventually progresses to end-stage renal disease (ESRD). Additionally, older patients with AKI suffer from an impaired quality of life and decreased functional status, both of which contribute to adverse outcomes. Maintaining adequate hydration and avoiding nephrotoxic agents are helpful in warding off AKI in elderly individuals. No proven treatment measures exist for AKI in elderly individuals except supportive therapy. A thorough understanding of the pathogenesis, etiology, clinical courses, complications, and prognosis of AKI in the elderly population is vital to preemptively reduce the incidence of AKI and hopefully create a better outcome. Copyright ? 2013, Asia Pacific League of Clinical Gerontology & Geriatrics. Published by Elsevier Taiwan LLC. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84897116085&doi=10.1016%2fj.jcgg.2013.04.002&partnerID=40&md5=293fa517b40ecd296c6f3bbcc3111332 https://scholars.lib.ntu.edu.tw/handle/123456789/578776 |
ISSN: | 2210-8335 | DOI: | 10.1016/j.jcgg.2013.04.002 | SDG/關鍵字: | acute kidney failure; aging; chronic kidney disease; clinical feature; disease association; disease classification; disease course; end stage renal disease; functional assessment; human; incidence; mortality; pathophysiology; priority journal; renal replacement therapy; review; risk factor; treatment planning |
顯示於: | 醫學系 |
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