https://scholars.lib.ntu.edu.tw/handle/123456789/579123
標題: | Lower Urinary Tract Symptoms and Uroflowmetry in Women With Type 2 Diabetes Mellitus With and Without Bladder Dysfunction | 作者: | Lee W.-C. Wu C.-C. HUEY-PEIR WU TONG-YUAN TAI |
公開日期: | 2007 | 卷: | 69 | 期: | 4 | 起(迄)頁: | 685-690 | 來源出版物: | Urology | 摘要: | Objectives: To study the presence of lower urinary tract symptoms and parameters of uroflowmetry in women with type 2 diabetes mellitus with and without bladder dysfunction versus healthy controls. Methods: After eliminating the possible confounders that might cause bladder dysfunction, 182 female patients at a diabetic clinic were evaluated by the American Urological Association Symptom Index (AUA-SI) questionnaire and uroflowmetry with postvoid residual (PVR) urine volume estimate. Their data were compared with the data from 197 healthy women, frequency-matched by age. Results: Using a cutoff value of bladder voiding efficiency of less than 75% with a PVR greater than 50 mL but less than 100 mL, a PVR greater than 100 mL, or a total volume greater than 500 mL, 47 patients (25.8%) were stratified as having bladder dysfunction. These patients had a significantly greater mean AUA-SI score (mean ± standard error of the mean 9.6 ± 0.8, P <0.001), as well as a lower maximum uroflow value (15.2 ± 1.2 mL/s, P <0.001) compared with the control groups. The odds ratio of each lower urinary tract symptom was significantly greater in this group, except for straining (P = 0.12). A high proportion with an intermittent uroflow pattern (odds ratio 4.42, P <0.001) was also noted. Compared with the healthy controls, the diabetic women had no bladder dysfunction and seemed unaffected by the lower urinary tract symptoms as defined by the AUA-SI scoring system, with the exception of nocturia (odds ratio 2.62, P = 0.006). Conclusions: Women with diabetes may have an increased risk of nocturia even without bladder dysfunction. A high AUA-SI score and lower maximum uroflow are likely to be good markers for diabetic bladder dysfunction. ? 2007 Elsevier Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34147108836&doi=10.1016%2fj.urology.2007.01.016&partnerID=40&md5=f7248c03dab2305398558b96c9dc2a3c https://scholars.lib.ntu.edu.tw/handle/123456789/579123 |
ISSN: | 0090-4295 | DOI: | 10.1016/j.urology.2007.01.016 | SDG/關鍵字: | adult; American Urological Association Symptom Index; article; bladder dysfunction; controlled study; female; human; lower urinary tract symptom; major clinical study; nocturia; non insulin dependent diabetes mellitus; outpatient department; patient assessment; postvoid residual urine volume; priority journal; questionnaire; scoring system; statistical significance; urine volume; uroflowmetry; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Middle Aged; Urethral Diseases; Urinary Bladder Diseases; Urodynamics |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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