https://scholars.lib.ntu.edu.tw/handle/123456789/579843
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | HSIU-HAO CHANG | en_US |
dc.contributor.author | Liu, Yen-Lin | en_US |
dc.contributor.author | MENG-YAO LU | en_US |
dc.contributor.author | SHIANN-TANG JOU | en_US |
dc.contributor.author | YUNG-LI YANG | en_US |
dc.contributor.author | Lin, Dong-Tsamn | en_US |
dc.contributor.author | Lin, Kai-Hsin | en_US |
dc.contributor.author | KAI-YUAN TZEN | en_US |
dc.contributor.author | RUOH-FANG YEN | en_US |
dc.contributor.author | CHING-CHU LU | en_US |
dc.contributor.author | CHIA-JU LIU | en_US |
dc.contributor.author | STEVEN SHINN-FORNG PENG | en_US |
dc.contributor.author | YUNG-MING JENG | en_US |
dc.contributor.author | Huang, Shiu-Feng | en_US |
dc.contributor.author | HSIN-YU LEE | en_US |
dc.contributor.author | Juan, Hsueh-Fen | en_US |
dc.contributor.author | MIN-CHUAN HUANG | en_US |
dc.contributor.author | Liao, Yung-Feng | en_US |
dc.contributor.author | Lee, Ya-Ling | en_US |
dc.contributor.author | WEN-MING HSU | en_US |
dc.date.accessioned | 2021-08-30T02:09:43Z | - |
dc.date.available | 2021-08-30T02:09:43Z | - |
dc.date.issued | 2017-01-17 | - |
dc.identifier.issn | 1949-2553 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/579843 | - |
dc.description.abstract | We assessed the impact of a multidisciplinary team care program on treatment outcomes in neuroblastoma patients. Newly diagnosed neuroblastoma patients received treatment under the Taiwan Pediatric Oncology Group (TPOG) N2002 protocol at the National Taiwan University Hospital beginning in 2002. A multidisciplinary team care approach that included nurse-led case management for patients treated under this protocol began in January 2010. Fifty-eight neuroblastoma patients, including 29 treated between 2002 and 2009 (Group 1) and 29 treated between 2010 and 2014 (Group 2), were enrolled in the study. The 5-year overall survival (OS) and event-free survival (EFS) rates for all 58 patients were 59% and 54.7%, respectively. Group 2 patients, who were treated after implementation of the multidisciplinary team care program, had better 3-year EFS (P = 0.046), but not OS (P = 0.16), rates than Group 1 patients. In a multivariate analysis, implementation of the multidisciplinary team approach was the only significant independent prognostic factor for neuroblastoma patients. In further subgroup analyses, the multidisciplinary team approach improved EFS, but not OS, in patients with stage 4 disease, those in the high-risk group, and those with non-MYCN amplified tumors. These data indicate a multidisciplinary team care approach improved survival outcomes in high-risk neuroblastoma patients. However, further investigation will be required to evaluate the long-term effects of this approach over longer follow-up periods. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Oncotarget | en_US |
dc.subject | chemotherapy; high-risk; multidisciplinary team care; neuroblastoma; outcomes | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | carboplatin; cyclophosphamide; doxorubicin; etoposide; adolescent; Article; cancer chemotherapy; cancer radiotherapy; cancer staging; case management; child; event free survival; high risk patient; high risk population; human; infant; major clinical study; male; multivariate analysis; neuroblastoma; newborn; overall survival; Taiwan; treatment outcome | - |
dc.title | A multidisciplinary team care approach improves outcomes in high-risk pediatric neuroblastoma patients | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.18632/oncotarget.13874 | - |
dc.identifier.pmid | 27966455 | - |
dc.identifier.scopus | 2-s2.0-85012004412 | - |
dc.identifier.url | https://scholars.lib.ntu.edu.tw/handle/123456789/405398 | - |
dc.relation.journalvolume | 8 | en_US |
dc.relation.journalissue | 3 | en_US |
dc.relation.pageend | 4372 | en_US |
item.fulltext | no fulltext | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Radiology | - |
crisitem.author.dept | Medical Imaging-NTUH | - |
crisitem.author.dept | Nuclear Medicine-NTUH | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Pathology-NTUH | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Life Science | - |
crisitem.author.dept | Center for Biotechnology | - |
crisitem.author.dept | Electrical Engineering | - |
crisitem.author.dept | Molecular and Cellular Biology | - |
crisitem.author.dept | Life Science | - |
crisitem.author.dept | Genome and Systems Biology Degree Program | - |
crisitem.author.dept | Office of Research and Development | - |
crisitem.author.dept | Anatomy and Cell Biology | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Surgery | - |
crisitem.author.orcid | 0000-0003-1832-8509 | - |
crisitem.author.orcid | 0000-0003-4461-9967 | - |
crisitem.author.orcid | 0000-0003-1483-0403 | - |
crisitem.author.orcid | 0000-0002-3598-7218 | - |
crisitem.author.orcid | 0000-0002-5657-8579 | - |
crisitem.author.orcid | 0000-0003-1648-6482 | - |
crisitem.author.orcid | 0000-0003-3114-582X | - |
crisitem.author.orcid | 0000-0003-1641-5617 | - |
crisitem.author.orcid | 0000-0002-8177-5187 | - |
crisitem.author.orcid | 0000-0002-3878-4491 | - |
crisitem.author.orcid | 0000-0002-1477-0183 | - |
crisitem.author.orcid | 0000-0003-4876-3309 | - |
crisitem.author.orcid | 0000-0002-0704-3447 | - |
crisitem.author.orcid | 0000-0002-5145-9538 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | Administrative Unit | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。