https://scholars.lib.ntu.edu.tw/handle/123456789/580954
標題: | Comparison of thin-film-transistor and photonic crystal protein sensors | 作者: | Huang J.-J. JIAN-JANG HUANG |
關鍵字: | Coenzymes; Fluidic devices; Refractory metal compounds; Semiconducting indium compounds; Thin film circuits; Thin films; Biochemical functions; Biochemical reactions; Biological science; Biotin-streptavidin; Exhaust conditions; Microfluidic channel; Streptavidin-biotin complex; TFT (thin film transistor); Thin film transistors | 公開日期: | 2019 | 卷: | Part F140-CLEO_Europe 2019 | 來源出版物: | Optics InfoBase Conference Papers | 摘要: | This talk is aiming on presenting two novel detecting schemes that were developed in our lab. First of all, we demonstrate a highly sensitive IGZO TFT (thin film transistor) with dual gate electrodes that detects electric charges of the target biomaterial. The TFT also functions as a transducer for signal readout. An IGZO TFT-based biosensor integrated with a microfluidic channel can be further used to monitor biochemical reactions between proteins and small molecules. Using Biotin-Streptavidin reaction as an example, the specific diffusion time of biotin, streptavidin, or streptavidin-biotin complex across the fluidic channel are benchmarked. By intentionally delaying the application of one specie to another, we can study properties of biochemical reactions, such as excess and exhaust conditions of the reactants, and the formation of the products while diffusing in the channel. The proposed TFT sensor provides an excellent platform in understanding the biochemical functions for the advance of biological science. ? 2019 IEEE |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85084530725&partnerID=40&md5=6294740d8fd4a56b22d1af4c9735a805 https://scholars.lib.ntu.edu.tw/handle/123456789/580954 |
顯示於: | 電機工程學系 |
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