https://scholars.lib.ntu.edu.tw/handle/123456789/581650
標題: | Idiopathic sclerosing orbital inflammation - A case series study | 作者: | Chen Y.-M. FUNG-RONG HU SHU-LANG LIAO |
關鍵字: | Debulking surgery; Idiopathic sclerosing orbital inflammation; Proptosis; Reduced visual acuity | 公開日期: | 2009 | 卷: | 224 | 期: | 1 | 起(迄)頁: | 55-58 | 來源出版物: | Ophthalmologica | 摘要: | Aims: It was the aim of this study to perform a review of the clinical features, treatments and outcomes of patients with idiopathic sclerosing orbital inflammation (ISOI) in Taiwan. Methods: All patients with histologically confirmed ISOI from 1995 to 2007 at the National Taiwan University Hospital were included. We reviewed the medical charts to see the clinical presentation, treatment modalities, treatment efficacy and final clinical status of these patients. Results: Six male and 3 female patients ranging in age from 33 to 82 years were included. The most common symptoms were pain and blurred vision (both 77.8%). Reduced visual acuity and proptosis were the most common signs (both 89%). Five patients received oral steroid treatment with/without pulse therapy combined with tissue removal, the response to which was good in 1 patient and partially effective in the other 4 patients. One patient received oral steroids and surgery, followed by radiotherapy, with only partial response. Patients with oral prednisolone or surgery only all had poor responses. Conclusion: ISOI is rare and also difficult to diagnose and manage. Early intervention with steroids/immunosuppressants combined with surgical debulking procedures may result in control or regression of this recalcitrant disease. Copyright ? 2009 S. Karger AG, Basel. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-68749091305&doi=10.1159%2f000235564&partnerID=40&md5=5e2a4b411c4c07c698e980751e67ad9e https://scholars.lib.ntu.edu.tw/handle/123456789/581650 |
ISSN: | 0030-3755 | DOI: | 10.1159/000235564 | SDG/關鍵字: | prednisolone; steroid; adult; aged; article; blurred vision; clinical article; clinical feature; cytoreductive surgery; drug pulse therapy; exophthalmos; female; health status; human; human tissue; idiopathic sclerosing orbital inflammation; male; medical record review; orbit disease; pain; symptom; Taiwan; treatment outcome; visual acuity; Administration, Oral; Adult; Aged; Aged, 80 and over; Biopsy; Combined Modality Therapy; Exophthalmos; Female; Fibrosis; Glucocorticoids; Humans; Male; Middle Aged; Orbital Pseudotumor; Prednisolone; Retrospective Studies; Tomography, X-Ray Computed; Vision Tests; Visual Acuity |
顯示於: | 醫學系 |
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