https://scholars.lib.ntu.edu.tw/handle/123456789/583176
標題: | Effect of Adenotonsillectomy on Ambulatory Blood Pressure in Pediatric Obstructive Sleep Apnea: 6-Month Follow-up Study | 作者: | Kang, Kun-Tai SHUENN-NAN CHIU CHE-YI LIN WEN-CHIN WENG PEI-LIN LEE WEI-CHUNG HSU |
公開日期: | 2019 | 出版社: | SAGE Publications Inc. | 卷: | 160 | 期: | 5 | 起(迄)頁: | 911-921 | 來源出版物: | Otolaryngology - Head and Neck Surgery (United States) | 摘要: | Objective: To investigate 24-hour ambulatory blood pressure changes 6 months after surgery among children with obstructive sleep apnea. Study Design: Prospective interventional study. Setting: Tertiary medical hospital. Subjects and Methods: Children aged 4 to 16 years with symptoms of obstructive sleep apnea (apnea-hypopnea index >1) were recruited. All children underwent adenotonsillectomy and postoperative polysomnography overnight. The 24-hour ambulatory blood pressure was measured before and 6 months after surgery. Results: The study cohort enrolled 124 children: mean (SD) age, 7.3 (3.1) years; 73% boys. After surgery, the apnea-hypopnea index significantly decreased from 13.3 (18.1) to 3.3 (7.2) events per hour (P <.001). Overall systolic blood pressure and diastolic blood pressure were not significantly different following surgery, while daytime systolic blood pressure was slightly increased (114.3 to 117.3 mm Hg, P <.01) postoperatively. The hypertensive group (n = 43) exhibited significantly decreased levels of overall diastolic, nighttime systolic, and nighttime diastolic blood pressure (P <.05), and 54% of hypertensive children became nonhypertensive after surgery. The nonhypertensive group (n = 81) showed slightly increased levels of nocturnal overall systolic, daytime systolic, and nighttime systolic blood pressure. A generalized linear mixed model revealed that children with hypertension had a greater decrease in systolic and diastolic ambulatory blood pressure during the daytime and nighttime (all P <.05) than those without hypertension. Conclusions: Ambulatory blood pressure changes after adenotonsillectomy among children with obstructive sleep apnea are minimal. The decrease in ambulatory blood pressure after surgery is more prominent for hypertensive children than nonhypertensive children. ? American Academy of Otolaryngology–Head and Neck Surgery Foundation 2019. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061216972&doi=10.1177%2f0194599818825462&partnerID=40&md5=a15377a1a45abb26c61b9f2839e15e80 https://scholars.lib.ntu.edu.tw/handle/123456789/583176 |
ISSN: | 0194-5998 | DOI: | 10.1177/0194599818825462 | SDG/關鍵字: | adenotonsillectomy; adolescent; apnea hypopnea index; Article; blood pressure monitoring; body mass; child; diastolic blood pressure; disease severity; female; follow up; heart rate; human; hypertension; major clinical study; male; oxygen saturation; polysomnography; prospective study; REM sleep; sleep disordered breathing; systolic blood pressure; tertiary care center; waist circumference; adenoidectomy; blood pressure; blood pressure monitoring; pathophysiology; physiology; preschool child; sleep disordered breathing; time factor; tonsillectomy; treatment outcome; Adenoidectomy; Adolescent; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Male; Polysomnography; Prospective Studies; Sleep Apnea, Obstructive; Time Factors; Tonsillectomy; Treatment Outcome |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。