https://scholars.lib.ntu.edu.tw/handle/123456789/583287
標題: | Differentiating metastatic lymph nodes in lung cancer patients based on endobronchial ultrasonography features | 作者: | CHING-KAI LIN LIH-YU CHANG KAI-LUN YU Wen Y.-F. Fan H.-J. CHAO-CHI HO |
公開日期: | 2018 | 出版社: | Societatea Romana de Ultrasonografie in Medicina si Biologie | 卷: | 20 | 期: | 2 | 起(迄)頁: | 154-158 | 來源出版物: | Medical Ultrasonography | 摘要: | Aim: The aim of this study was to identify easy and relatively effective ultrasound criteria for metastatic mediastinal lymph node prediction. Materials and methods: A retrospective chart review of patients who underwent endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) from March 2014 to September 2016 was performed. We used the following EBUS sonographic features for metastatic lymph node prediction: 1) length of the short axis, 2) shape, 3) margin, 4) echogenicity, 5) central hilar structure, and 6) coagulation necrosis sign. These sonographic findings were compared with the final pathology results or clinical follow-up. Results: A total of 227 lymph nodes were retrospectively evaluated in 133 lung cancer patients; 72% of the lymph nodes had been proven to be malignant metastasis. Logistic regression analysis revealed that the length of the short axis, shape, margin, and echogenicity were independent predictive factors for metastasis. We developed a sum score based on these four sonographic features. A larger sum score trended toward a greater possibility of malignancy. If all four predictive factors were preserved, the diagnostic accuracy, the value of the specificity and the positive predictive value of the sonographic feature would be higher than 90%. Conclusions: The sonographic features of EBUS are valuable tools in predicting metastatic lymph nodes in lung cancer patients. ? 2017, Societatea Romana de Ultrasonografie in Medicina si Biologie. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046830747&doi=10.11152%2fmu-1282&partnerID=40&md5=f43cc1d411253e9d3341d889619b5c51 https://scholars.lib.ntu.edu.tw/handle/123456789/583287 |
ISSN: | 1844-4172 | DOI: | 10.11152/mu-1282 | SDG/關鍵字: | adult; aged; Article; cancer patient; clinical evaluation; clinical feature; controlled study; diagnostic accuracy; diagnostic test accuracy study; endobronchial ultrasonography; female; follow up; histopathology; human; logistic regression analysis; lung cancer; lymph node metastasis; major clinical study; male; mediastinum lymph node; medical record review; prediction; predictive value; retrospective study; scoring system; sensitivity and specificity; transbronchial aspiration; bronchoscopy; diagnostic imaging; differential diagnosis; echography; endoscopic ultrasonography; fine needle aspiration biopsy; interventional ultrasonography; lung tumor; lymph node; lymph node metastasis; mediastinum; middle aged; pathology; procedures; very elderly; Adult; Aged; Aged, 80 and over; Biopsy, Fine-Needle; Bronchoscopy; Diagnosis, Differential; Endosonography; Female; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Mediastinum; Middle Aged; Retrospective Studies; Ultrasonography; Ultrasonography, Interventional |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。