https://scholars.lib.ntu.edu.tw/handle/123456789/585820
標題: | Brain tumor presenting as anorexia nervosa in a 19-year-old man | 作者: | Lin L. SHIH-CHENG LIAO Lee Y.-J. Tseng M.-C. MING-BEEN LEE |
公開日期: | 2003 | 卷: | 102 | 期: | 10 | 起(迄)頁: | 737-740 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Slow-growing brain tumors can produce disturbances of food intake and endocrine dysfunction. We report a case of slow-growing midline brain tumor in a patient with clinical presentation of anorexia nervosa (AN). A 19-year-old man was referred from a general practitioner to a psychiatric clinic due to illness behavior and psychophathological characteristics of AN. His body weight had decreased from 52 kg to 40 kg within 6 months. Laboratory tests showed hypernatremia (160 mmol/L), adrenal insufficiency (adrenocorticotrophic hormone, 11.4 pg/mL; 8 am cortisol, 1.4 μg/dL; 4 pm cortisol, 11.4 μg/dL)and hypogonadotropic hypogonadism (testosterone < 0.5 ng/mL, follicle-stimulating hormone < 0.1 mIU/mL, luteinizing hormone < 0.7 mIU/mL). Brain magnetic resonance imaging showed an extensive mass lesion at suprasellar, hypothalamic region, third ventricle, pineal region, lateral ventricle, and corpus callosum. Owing to central herniation during physical assessment, he died of unknown intracranial pathology. This case suggests that an intracranial tumor near the hypothalamus should be included in the differential diagnosis of AN. Any male adolescent with the clinical impression of AN should receive periodic re-evaluation, including neurological, endocrinological and, if necessary, neuroimaging study. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-1342266975&partnerID=40&md5=d95199926903d573dbf92ba07138c9ad https://scholars.lib.ntu.edu.tw/handle/123456789/585820 |
ISSN: | 9296646 | SDG/關鍵字: | corticotropin; follitropin; hydrocortisone; luteinizing hormone; testosterone; adrenal cortex insufficiency; adrenal insufficiency; adult; anorexia nervosa; article; body weight; brain hernia; brain third ventricle; brain tumor; case report; clinical feature; corpus callosum; corticotropin blood level; differential diagnosis; fatality; follitropin blood level; human; hydrocephalus; hydrocortisone blood level; hypernatremia; hypogonadism; hypogonadotropic hypogonadism; hypothalamus tumor; illness behavior; laboratory test; lateral brain ventricle; luteinizing hormone blood level; male; neurologic examination; nuclear magnetic resonance imaging; pineal body tumor; testosterone blood level; Adrenal Insufficiency; Adult; Anorexia Nervosa; Brain Neoplasms; Diagnosis, Differential; Fatal Outcome; Humans; Hydrocephalus; Hypernatremia; Hypogonadism; Male |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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