https://scholars.lib.ntu.edu.tw/handle/123456789/587215
標題: | Salvage surgery for recurrent nasopharyngeal carcinoma | 作者: | Hsu M.-M JENG-YUH KO Sheen T.-S Chang Y.-L. |
公開日期: | 1997 | 出版社: | American Medical Association | 卷: | 123 | 期: | 3 | 起(迄)頁: | 305-309 | 來源出版物: | Archives of Otolaryngology - Head and Neck Surgery | 摘要: | Objective: To assess the efficacy of salvage surgery for patients with recurrent nasopharyngeal carcinoma (NPC) at the primary site after radiotherapy. Design: Retrospective analysis of 24 patients treated by transpalatal, transmaxillary, or transmandibular approach to resect the recurrent tumor, with maximum follow-up of 50 months. Setting: Academic tertiary referral center. Results: Radiotherapy before salvage surgery included 1 to 3 courses of radiation to the nasopharynx, with doses ranging from 60 to 190 Gy. Eighteen (75%) of the patients relapsed within 2 years, and 6 (25%) relapsed more than 6 years after the last irradiation. In 4 of 6 late-relapsing cases, the histopathological type changed to keratinizing squamous cell carcinoma, which is rare in cases of NPC in Taiwan. Fourteen patients (58%) survived for 8 to 50 months after surgery (median, 18 months). The surgical complications were tolerable. Conclusions: Salvage surgery is feasible in selected patients with recurrent disease at the primary site. Thus, we can offer alternative retreatment in addition to external irradiation for patients with recurrent NPC. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030991111&doi=10.1001%2farchotol.1997.01900030087011&partnerID=40&md5=d79e5e55d83f43a9c1532ceff3164484 https://scholars.lib.ntu.edu.tw/handle/123456789/587215 |
ISSN: | 0886-4470 | DOI: | 10.1001/archotol.1997.01900030087011 | SDG/關鍵字: | adult; aged; article; cancer radiotherapy; cancer recurrence; clinical article; female; human; male; nasopharynx carcinoma; salvage therapy; surgical approach; surgical technique |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。