https://scholars.lib.ntu.edu.tw/handle/123456789/588882
標題: | Jarisch-Herxheimer reaction after penicillin therapy among patients with syphilis in the era of the HIV infection epidemic: Incidence and risk factors | 作者: | Yang C.-J. Lee N.-Y. Lin Y.-H. Lee H.-C. Ko W.-C. Liao C.-H. Wu C.-H. Hsieh C.-Y. Wu P.-Y. Liu W.-C. Chang Y.-C. CHIEN-CHING HUNG |
公開日期: | 2010 | 卷: | 51 | 期: | 8 | 起(迄)頁: | 976-979 | 來源出版物: | Clinical Infectious Diseases | 摘要: | The incidence of and risk factors for Jarisch-Herxheimer (JH) reaction were investigated prospectively among 240 human immunodeficiency virus (HIV)-infected and 115 HIV-uninfected patients with syphilis who received penicillin treatment. The overall rate of JH reaction was 31.5% (34.6% in HIV-infected patients and 25.2% in HIV-uninfected patients). In multivariate analysis, risk factors for JH reaction included high rapid plasma reagin (RPR) titers (per log2 RPR increase, risk ratio [RR], 1.19; 95% confidence interval [CI], 1.04-1.37), early syphilis (RR, 8.59; 95% CI, 4.75-15.56), and prior penicillin treatment (RR, 0.39; 95% CI, 0.20-0.78). ? 2010 by the Infectious Diseases Society of America. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957830514&doi=10.1086%2f656419&partnerID=40&md5=479b1c2453088b9e22b36757bdd3cfec https://scholars.lib.ntu.edu.tw/handle/123456789/588882 |
ISSN: | 1058-4838 | DOI: | 10.1086/656419 | SDG/關鍵字: | penicillin G; reaginic antibody; adult; antibody blood level; article; clinical trial; confidence interval; female; Herxheimer reaction; human; Human immunodeficiency virus infection; major clinical study; male; multivariate analysis; priority journal; prospective study; risk factor; syphilis; Adolescent; Adult; Anti-Bacterial Agents; Exanthema; Female; Fever; HIV Infections; Humans; Incidence; Male; Middle Aged; Penicillins; Prospective Studies; Reagins; Risk Factors; Syphilis; Vasodilation; Young Adult |
顯示於: | 醫學系 |
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