https://scholars.lib.ntu.edu.tw/handle/123456789/590646
Title: | Preclinical evaluation of PEGylated liposomal doxorubicin as an effective radiosensitizer in chemoradiotherapy for lung cancer | Authors: | JENNY LING-YU CHEN Pan, Chun-Kai Lin, Yu-Li Tsai, Ching-Yi YU-SEN HUANG WEN-CHI YANG FENG-MING HSU SUNG-HSIN KUO MING-JIUM SHIEH |
Keywords: | Antitumor effect; Apoptosis; Mouse model; Neoplasm; Radiosensitization | Issue Date: | Dec-2021 | Journal Volume: | 197 | Journal Issue: | 12 | Source: | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] | Abstract: | Development of a safe and effective systemic chemotherapeutic agent for concurrent administration with definitive thoracic radiotherapy remains a major goal of lung cancer management. The synergistic effect of PEGylated liposomal doxorubicin and irradiation was evaluated in lung cancer cell lines both in vitro and in vivo. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/590646 | ISSN: | 01797158 | DOI: | 10.1007/s00066-021-01835-9 | SDG/Keyword: | caspase 3; doxorubicin; histone H2AX; lipo dox; A-549 cell line; animal cell; animal experiment; animal model; animal tissue; antineoplastic activity; apoptosis; Article; BEAS-2B cell line; cardiac muscle cell; cell proliferation; cell survival; chemoradi |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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