https://scholars.lib.ntu.edu.tw/handle/123456789/593303
Title: | Nonsecreting immunoproliferative small intestinal disease: Report of a case | Authors: | CHUN-JEN LIU PEI-MING YANG Wong J.-M. Chiang I.-P. Wang T.-H. DING-SHINN CHEN |
Issue Date: | 1997 | Journal Volume: | 14 | Journal Issue: | 3 | Start page/Pages: | 250-257 | Source: | Gastroenterological Journal of Taiwan | Abstract: | Immunoproliferative small intestinal disease has rarely been reported in Taiwan. A 31-year-old man had suffered from severe diarrhea and malabsorption for one year prior to admission. Jejunal biopsy through enteroscopic examination revealed atrophic villi and dense infiltration in lamina propria by lymphocytes, with extension beyond the layer of muscularis mucosa. Alpha- chain protein was not demonstrated in the patient's serum, urine, diluted duodenal juice, and jejunal biopsy tissue. He was treated with metronidazole for three weeks per os and tetracycline for four months. Frequency of diarrhea decreased two weeks after treatment. Clinical symptoms and signs of malabsorption improved gradually. However, lymphadenopathies developed on both nuchal, axillary, and inguinal areas after a ten-month symptom-free period. The diagnosis of non-Hodgkin's lymphoma, diffuse large B cell type, stage III a, was made following systemic work-up. Systemic chemotherapy was administered with complete clinical remission. To our knowledge, this is the first case of nonsecreting immunoproliferative small intestinal disease reported in Taiwan. Furthermore, immunoproliferative small intestinal disease should be considered in the differential diagnosis of longterm diarrhea, especially in the presence of malabsorption. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031462703&partnerID=40&md5=72756ed042ffe4ac425869127c50e103 https://scholars.lib.ntu.edu.tw/handle/123456789/593303 |
ISSN: | 1013-7696 | SDG/Keyword: | antineoplastic agent; cyclophosphamide; doxorubicin; methylprednisolone; metronidazole; tetracycline; vincristine; adult; article; case report; diarrhea; human; intestine biopsy; intestine lymphoma; intravenous drug administration; lymphadenopathy; malabsorption; male; nonhodgkin lymphoma; oral drug administration |
Appears in Collections: | 臨床醫學研究所 |
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