https://scholars.lib.ntu.edu.tw/handle/123456789/593654
標題: | Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse | 作者: | Kung, Yi KUAN-YU CHEN Liao, Wei-Hao Hsu, Yi-Hua CHUEH-HUNG WU MING-YEN HSIAO ABEL PO-HAO HUANG WEN-SHIANG CHEN |
關鍵字: | Blood-cerebrospinal fluid barrier; Blood–brain barrier; Central nervous system; Glioblastoma multiforme; Leptomeningeal carcinomatosis; Low-energy extracorporeal focused shockwave pulse | 公開日期: | 6-一月-2022 | 出版社: | BMC | 卷: | 19 | 期: | 1 | 來源出版物: | Fluids and barriers of the CNS | 摘要: | The blood-cerebrospinal fluid (CSF) barrier (BCSFB) is critically important to the pathophysiology of the central nervous system (CNS). However, this barrier prevents the safe transmission of beneficial drugs from the blood to the CSF and thus the spinal cord and brain, limiting their effectiveness in treating a variety of CNS diseases. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/593654 | ISSN: | 2045-8118 | DOI: | 10.1186/s12987-021-00303-x |
顯示於: | 醫學系 |
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