https://scholars.lib.ntu.edu.tw/handle/123456789/594004
標題: | Abnormal in vitro CXCR2 modulation and defective cationic ion transporter expression on polymorphonuclear neutrophils responsible for hyporesponsiveness to IL-8 stimulation in patients with active systemic lupus erythematosus | 作者: | SONG-CHOU HSIEH Wu T.-H. Tsai C.-Y. KO-JEN LI Lu M.-C. Wu C.-H. CHIA-LI YU |
關鍵字: | systemic lupus erythematosus; polymorphonuclear neutrophil; hyporesponsiveness; CXCR2 modulation; membrane potential; cationic ion transporters; HUMAN INTERLEUKIN-8 RECEPTOR; ACTIVATING PEPTIDE-2; CHEMOKINE RECEPTORS; SIGNAL-TRANSDUCTION; DISEASE-ACTIVITY; CELL ACTIVATION; DOWN-REGULATION; GRO-ALPHA; CHANNEL; PROTEIN | 公開日期: | 二月-2008 | 出版社: | OXFORD UNIV PRESS | 卷: | 47 | 期: | 2 | 起(迄)頁: | 150 | 來源出版物: | Rheumatology (Oxford, England) | 摘要: | To elucidate the molecular basis of hyporesponsiveness of polymorphonuclear neutrophils (PMN) to interleukin-8 (IL-8) stimulation in patients with active SLE. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/594004 | ISSN: | 1462-0324 | DOI: | 10.1093/rheumatology/kem320 | SDG/關鍵字: | adenosine triphosphatase (potassium sodium); chemokine receptor CXCR2; interleukin 8; potassium channel; renal epithelial sodium channel; renal outer medullary epithelial potassium channel 1; sodium channel; unclassified drug; article; binding affinity; cation transport; cell surface; controlled study; down regulation; enzyme immunoassay; flow cytometry; gene expression regulation; human; human cell; immunomodulation; in vitro study; ion transport; membrane potential; nerve cell; neutrophil; priority journal; reverse transcription polymerase chain reaction; Scatchard plot; systemic lupus erythematosus; Female; Flow Cytometry; Gene Expression Regulation; Humans; Interleukin-8; Lipopolysaccharides; Lupus Erythematosus, Systemic; Male; Neutrophils; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。