https://scholars.lib.ntu.edu.tw/handle/123456789/594521
標題: | Insomnia and the risk of atrial fibrillation: A population-based cohort study | 作者: | Lee H.-H. Chen Y.-C. JIEN-JIUN CHEN Lo S.-H. Yue Leon Guo Hu H.-Y. |
公開日期: | 2017 | 出版社: | Republic of China Society of Cardiology | 卷: | 33 | 期: | 2 | 起(迄)頁: | 165-172 | 來源出版物: | Acta Cardiologica Sinica | 摘要: | Background: Although advancements in the treatment of atrial fibrillation have improved patient prognosis for this persistent condition, interest in atrial fibrillation development is growing. Of note is the fact that additional attention is being focused on the accompanying effect of insomnia. The aim of the study was to investigate the effects of insomnia on the risk of atrial fibrillation development. Methods: This was a nationwide population-based retrospective cohort study using data fromthe Taiwan National health Insurance Research Database. We analyzed 64,421 insomnia cases and 128,842 matched controls without insomnia from January 1, 2000, to December 31, 2010. A Cox regression model was used to estimate the adjusted hazard ratios (HRs) and 95% confidence intervals (CI) for atrial fibrillation development. Results: During the follow-up period, the incidence of atrial fibrillation development was significantly higher in the insomnia cases than in the comparison cohort (2.6% vs. 2.3%, p < 0.001). Insomnia was associated with an increased risk of atrial fibrillation (HR = 1.08, 95% CI: 1.01-1.14).Males, those > 65 years of age, and patients with peripheral artery disease who have insomnia had a higher rate of atrial fibrillation development. Conclusions: The findings of this nationwide analysis support the hypothesis that insomnia is associated with a significant risk of atrial fibrillation development. ? 2017, Republic of China Society of Cardiology. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85015699309&doi=10.6515%2fACS20160611B&partnerID=40&md5=48f861d3f2584d71a600d1425e5c309e https://scholars.lib.ntu.edu.tw/handle/123456789/594521 |
ISSN: | 1011-6842 | DOI: | 10.6515/ACS20160611B | SDG/關鍵字: | adult; Article; atrial fibrillation; bipolar disorder; chronic kidney failure; clinical outcome; comorbidity; congestive heart failure; controlled study; coronary artery disease; depression; diabetes mellitus; disease free survival; dyslipidemia; female; hospitalization; human; hypertension; ICD-9-CM; insomnia; major clinical study; male; peripheral occlusive artery disease; retrospective study; risk; sleep disordered breathing; valvular heart disease |
顯示於: | 醫學系 |
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