https://scholars.lib.ntu.edu.tw/handle/123456789/597153
標題: | Human T-lymphotropic virus type II infection in Vietnamese thalassemic patients | 作者: | Lin M.T. Nguyen B.T. Binh T.V. Be T.V. Chiang T.Y. LI-HUI TSENG YA-CHIEN YANG Lin K.H. Chen Y.C. |
公開日期: | 1997 | 卷: | 142 | 期: | 7 | 起(迄)頁: | 1429-1440 | 來源出版物: | Archives of Virology | 摘要: | Anti-human T-lymphotropic virus type I/II (HTLV-I/II) antibodies were screened by particle agglutination test in a total of 66 patients with thalassemia major who received multiple transfusion from paid donors at the Blood Transfusion Hematology Center of Ho Chi Minh City in South Vietnam. HTLV-II infection was confirmed in 6 patients (9.1%) by Western blot analysis and/or polymerase chain reaction. Phylogenetic analysis revealed that long terminal repeat sequences of HTLV-II proviruses from 5 thalassemic patients in Vietnam belonged to the same phylogenetic subgroup of HTLV-IIb as those from intravenous drug abusers in North America and Europe. These data shed light on the route of introducing HTLV-II into Vietnam. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030746288&doi=10.1007%2fs007050050170&partnerID=40&md5=bb4d3767e29bb7c66f1eba9dbb2124e4 https://scholars.lib.ntu.edu.tw/handle/123456789/597153 |
ISSN: | 0304-8608 | DOI: | 10.1007/s007050050170 | SDG/關鍵字: | Human T cell leukemia virus antibody; human T cell leukemia virus type II protein gp21; human T-cell leukemia virus type-II protein gp21; oncoprotein; virus envelope protein; adolescent; agglutination test; article; beta thalassemia; blood; child; classification; disease transmission; envelope gene; female; genetics; human; Human T cell leukemia virus 2; Human T cell leukemia virus infection; infant; male; molecular genetics; nucleotide repeat; nucleotide sequence; phylogeny; polymerase chain reaction; preschool child; prevalence; provirus; restriction fragment length polymorphism; Viet Nam; virology; Adolescent; Agglutination Tests; Base Sequence; beta-Thalassemia; Child; Child, Preschool; Female; Gene Products, env; Genes, env; HTLV-II Antibodies; HTLV-II Infections; Human T-lymphotropic virus 2; Humans; Infant; Male; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Proviruses; Repetitive Sequences, Nucleic Acid; Retroviridae Proteins, Oncogenic; Vietnam; HTLV; htlv ii; Human immunodeficiency virus; Human T-lymphotropic virus 2 |
顯示於: | 基因體暨蛋白體醫學研究所 |
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