https://scholars.lib.ntu.edu.tw/handle/123456789/604003
標題: | Serum Creatinine Reference Limits in Pediatric Population-A Single Center Electronic Health Record-Based Database in Taiwan | 作者: | GWO-TSANN CHUANG I-JUNG TSAI Tsau, Yong-Kwei |
關鍵字: | acute kidney injury; adolescents; pediatrics; renal function; serum creatinine | 公開日期: | 2021 | 出版社: | FRONTIERS MEDIA SA | 卷: | 9 | 來源出版物: | Frontiers in pediatrics | 摘要: | Objective: To assess age- and sex-specific serum creatinine levels in a pediatric population using a hospital-based database in Taiwan. Study Design: Data on serum creatinine levels were obtained from the National Taiwan University Hospital-integrated Medical Database (NTUH-iMD). Due to the possibility of having acute kidney injury or chronic kidney disease, individuals with multiple serum creatinine measurements were excluded, and outliers in each age- and sex-specific group were also subsequently removed. The remaining creatinine measurements in each group were analyzed, and 95% reference limits were established. Results: Serum creatinine data of individuals aged between 1 month and 18 years from May 2011 to January 2018 were retrieved. After applying the exclusion criteria, 27,911 individuals with a single corresponding serum creatinine measurement were enrolled. Creatinine level reference limits for each age- and sex-specific group were generated. The upper reference limits (URLs), which are particularly useful in clinical practice, followed the natural trend of increasing serum creatinine with age. Conclusion: We generated serum creatinine reference limits from a single hospital-integrated medical database in Taiwan for different age- and sex-specific groups of children. Our results will aid physicians in clinical practice regarding renal function evaluation, especially for patients without a recent baseline serum creatinine level. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/604003 | ISSN: | 2296-2360 | DOI: | 10.3389/fped.2021.793446 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。