https://scholars.lib.ntu.edu.tw/handle/123456789/608096
標題: | Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications | 作者: | YUAN LUO Tseng, Ming Lun Vyas, Sunil Kuo, Hsin Yu Chu, Cheng Hung Chen, Mu Ku Hsiang-Chieh Lee WEN-PIN CHEN Su, Vin-Cent Shi, Xu Misawa, Hiroaki Tsai, Din Ping PAN-CHYR YANG |
關鍵字: | abrupt autofocusing beam; laser surgery; metasurfaces | 公開日期: | 四月-2022 | 出版社: | WILEY-V C H VERLAG GMBH | 卷: | 6 | 期: | 4 | 來源出版物: | Small methods | 摘要: | Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125187854&doi=10.1002%2fsmtd.202101228&partnerID=40&md5=b20706d432598daee8e5be4ea231f13f | ISSN: | 2366-9608 | DOI: | 10.1002/smtd.202101228 | SDG/關鍵字: | Medical applications; Optical tomography; Abrupt autofocusing beam; Auto-focusing; Beam parameter; Biomedical applications; Metasurface; Nano scale; Optical energy; Property; Region-of-interest; Regions of interest; Laser surgery; animal experiment; animal tissue; article; biomedicine; controlled study; ex vivo study; fluorescence; heart; laser coagulation; laser surgery; male; mouse; nonhuman; optical coherence tomography; optics; pig; skin |
顯示於: | 醫學系 |
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