https://scholars.lib.ntu.edu.tw/handle/123456789/610507
標題: | Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients | 作者: | CHIH-WEI SUNG KAO-LANG LIU HSIU-PO WANG Chen, I-Chung EDWARD PEI-CHUAN HUANG WAN-CHING LIEN CHIEN-HUA HUANG |
關鍵字: | ABSCESS FORMATION; TERM MORTALITY; MANAGEMENT; YOUNG; DISEASE; NEED | 公開日期: | 2022 | 出版社: | NATURE PORTFOLIO | 卷: | 12 | 期: | 1 | 來源出版物: | Scientific reports | 摘要: | Evidence regarding the recurrence of diverticulitis is limited in Asian patients. This study aims to investigate recurrence rates and identify predictive factors for the recurrence of diverticulitis following successful nonoperative treatment in Asian patients. A multicenter, retrospective cohort study was conducted between 2012 and 2018. Adult patients with computed tomography (CT)-proven colonic diverticulitis were included. The primary outcome was the recurrence of diverticulitis, which was defined as another episode of occurrence of the infection after index hospital stay. Cumulative recurrence rates were calculated using the Kaplan-Meier method. Cox regression models were employed to identify parameters that significantly and independently predicted recurrence. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated. A total of 929 patients were included. Diverticulitis in the cecum/ascending occurred in 675 (72.6%) patients. The average follow-up period was 651 days. Recurrence was observed in 115 (12.4%) patients and most significantly observed in patients with sigmoid diverticulitis (HR, 2.24; 95% CIs 1.59-3.97), followed by those with descending colon diverticulitis (HR, 1.92; 95% CIs 1.17-3.25). Although most of the Asian patients had right-sided colonic diverticulitis, those with sigmoid diverticulitis had the highest risk of recurrence. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/610507 | ISSN: | 2045-2322 | DOI: | 10.1038/s41598-022-08708-w |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。