https://scholars.lib.ntu.edu.tw/handle/123456789/611714
標題: | Two-Way Coupling Between 1D Blood Flow and 3D Tissue Perfusion Models | 作者: | Padmos R.M. J?zsa T.I. El-Bouri W.K. Z?vodszky G. Payne S.J. Hoekstra A.G. STEPHEN JOHN PAYNE |
關鍵字: | Blood;Hemodynamics;One dimensional;Tissue;Arterial blood;Coupled modeling;Coupling resistance;Multiple scale;Perfusion models;Retrograde flow;Tissue perfusion;Two-way coupling;Tissue engineering | 公開日期: | 2021 | 卷: | 12744 LNCS | 起(迄)頁: | 670-683 | 來源出版物: | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | 摘要: | Accurately predicting brain tissue perfusion and infarct volume after an acute ischaemic stroke requires the two-way coupling of perfusion models on multiple scales. We present a method for such two-way coupling of a one-dimensional arterial blood flow model and a three-dimensional tissue perfusion model. The two-way coupling occurs through the pial surface, where the pressure drop between the models is captured using a coupling resistance. The two-way coupled model is used to simulate arterial blood flow and tissue perfusion during an acute ischaemic stroke. Infarct volume is estimated by setting a threshold on the perfusion change. By two-way coupling these two models, the effect of retrograde flow and its effect on tissue perfusion and infarct volume can be captured. ? 2021, Springer Nature Switzerland AG. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111392336&doi=10.1007%2f978-3-030-77967-2_56&partnerID=40&md5=8930670cc8a7a8c2bd743f5aeebf0fec https://scholars.lib.ntu.edu.tw/handle/123456789/611714 |
DOI: | 10.1007/978-3-030-77967-2_56 |
顯示於: | 應用力學研究所 |
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