https://scholars.lib.ntu.edu.tw/handle/123456789/616644
標題: | Quantitative analysis of dynamic power doppler sonograms for patients with thyroid nodules | 作者: | MING-HSUN WU CHIUNG-NIEN CHEN KUEN-YUAN CHEN MING-CHIH HO HAO-CHIH TAI Chung, Yuan-Chang Lo, Chan-Peng ARGON CHEN KING-JEN CHANG |
關鍵字: | Computer-aided detection;Power Doppler;Thyroid cancer;Vascular index;Vascularity | 公開日期: | 2013 | 出版社: | Elsevier USA | 卷: | 39 | 期: | 9 | 起(迄)頁: | 1543-1551 | 來源出版物: | Ultrasound in Medicine and Biology | 摘要: | To clarify and determine whether power Doppler sonograms are useful for the detection of malignant thyroid nodules, a computerized quantification method was used to evaluate the vascular density of a thyroid nodule in a prospective setting. Sonographic power Doppler images were collected in consecutive frames (45 frames of images), and a proprietary program (AmCAD-UV) was implemented using methods proposed in this article automatically calculated a quantified power Doppler vascular index (PDVI). The minimum PDVI value (PDVImin) was suggested as a measure of the vascular density of the nodule. The vascular densities of the peripheral and central areas of the nodule, referred to as central PDVImin and Ring PDVImin, respectively, were also evaluated. For 238 tumors (79 malignant and 159 benign) from 208 patients, all of the proposed indices of benign lesions were significantly higher than those of the malignant lesions. The area under the receiver operating characteristic curve (AUC) reaches 71% with the PDVImin. When the vascular patterns were further classified into intra-nodular and peripheral vascularity types, no vascularity type was observed significantly more frequently in malignant nodules than in benign nodules. These proposed computerized vascular indices provide a quantification method to objectively evaluate thyroid nodules and have potential as predictors of thyroid malignancy. The conventional vascular characterizations of malign nodules, that is, more vessels are observed in malignant nodules than in benign nodules, are shown to be unreliable in our study. Instead, a higher value of the quantified power Doppler vascular density was observed in benign nodules. © 2013 World Federation for Ultrasound in Medicine & Biology. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881662886&doi=10.1016%2fj.ultrasmedbio.2013.03.009&partnerID=40&md5=9977ebbd0f2847387501d4c6434d577c https://scholars.lib.ntu.edu.tw/handle/123456789/616644 |
ISSN: | 0301-5629 | DOI: | 10.1016/j.ultrasmedbio.2013.03.009 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。