https://scholars.lib.ntu.edu.tw/handle/123456789/620486
標題: | Nephrotoxins and acute kidney injury – The consensus of the Taiwan acute kidney injury Task Force | 作者: | Huang, Wei-Chun Wang, Mei-Tzu TAI-SHUAN LAI Lee, Kuo-Hua Shao, Shih-Chieh Chen, Chien-Hao Su, Chien-Hao Chen, Yih-Ting Sung, Junne-Ming Chen, Yung-Chang |
關鍵字: | Acute kidney injuries; Contrast; Nephrotoxicity | 公開日期: | 五月-2022 | 出版社: | ELSEVIER TAIWAN | 卷: | 121 | 期: | 5 | 起(迄)頁: | 886 | 來源出版物: | Journal of the Formosan Medical Association = Taiwan yi zhi | 摘要: | The Taiwan Acute Kidney Injury (AKI) Task Force conducted a review of data and developed a consensus regarding nephrotoxins and AKI. This consensus covers: (1) contrast-associated AKI; (2) drug-induced nephrotoxicity; (3) prevention of drug-associated AKI; (4) follow up after AKI; (5) re-initiation of medication after AKI. Strategies for the avoidance of contrast media related AKI, including peri-procedural hydration, sodium bicarbonate solutions, oral N-acetylcysteine, and iso-osmolar/low-osmolar non-ionic iodinated contrast media have been recommended, given the respective evidence levels. Regarding anticoagulants, both warfarin and new oral anticoagulants have potential nephrotoxicity, and dosage should be reduced if renal pathology exam proves renal injury. Recommended strategies to prevent drug related AKI have included assessment of 5R/(6R) reactions - risk, recognition, response, renal support, rehabilitation and (research), use of AKI alert system and computerized decision support. In terms of antibiotics-associated AKI, avoiding concomitant administration of vancomycin and piperacillin-tazobactam, monitoring vancomycin trough level, switching from vancomycin to teicoplanin in high-risk patients, and replacing conventional amphotericin B with lipid-based amphotericin B have been shown to reduce drug related AKI. With respect to non-steroidal anti-inflammatory drug associated AKI, it is recommended to use these drugs cautiously in the elderly and in patients receiving renin-angiotensin-aldosterone system inhibitors/diuretics triple combinations. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/620486 | ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2021.12.007 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。