https://scholars.lib.ntu.edu.tw/handle/123456789/620597
標題: | Double Nutri (Liposomal Encapsulation) Enhances Bioavailability of Vitamin C and Extends Its Half-Life in Plasma | 作者: | Chiung-Jung Wen Chiang, Chi-Fu Lee, Chung-Sheng Lin, Yung-Hsiang JAW-SHIUN TSAI |
關鍵字: | Antioxidant; Bioavailability; Liposome; Vitamin C; Food Processing; ASCORBIC-ACID; PHARMACOKINETICS; NANOLIPOSOMES | 公開日期: | 1-三月-2022 | 出版社: | AMER SCIENTIFIC PUBLISHERS | 卷: | 18 | 期: | 3 | 起(迄)頁: | 922 | 來源出版物: | Journal of biomedical nanotechnology | 摘要: | Vitamin C is an important antioxidant in the human body that plays a role in many body functions. Liposomal encapsulation is a technology commonly used in food processing and medicine. This study determines whether Double Nutri (liposomal encapsulation) increases the absorption rate for vitamin C supplementation. Subjects enrolled in this study took vitamin C without liposome; then, 14 d washout was given with liposomal process A vitamin C. After 14 d washout, the subjects took liposomal process B vitamin C (Double Nutri) was given. After taking the test sample, the vitamin C concentration in venous blood was measured from the baseline (0 h), 0.5, 1, 2, 3, 4, and 8 h. Eleven healthy subjects were recruited for three tests. The vitamin C concentration for liposomal process B vitamin C (Double Nutri) group is higher (7.26±3.52, p<0.01) than that for the liposomal process A vitamin C group (6.41±3.80, p<0.05) and for vitamin C without liposome (2.21±4.07). This shows that Double Nutri has better bioavailability and can last up in the body to 8 hours. In addition, this study shows that Double Nutri increases the half-life of vitamin C in plasma and has higher bioavailability. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/620597 | ISSN: | 1550-7033 | DOI: | 10.1166/jbn.2022.3274 |
顯示於: | 醫學系 |
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