https://scholars.lib.ntu.edu.tw/handle/123456789/621250
標題: | Non-immune functions of inflammatory cytokines targeted by anti-psoriatic biologics: a review | 作者: | Lee, Tung-Lin TSEN-FANG TSAI |
關鍵字: | Biologic agents; Inflammatory cytokines; Psoriasis; Psoriasis-related comorbidities | 公開日期: | 二月-2022 | 出版社: | SPRINGER BASEL AG | 卷: | 71 | 期: | 2 | 起(迄)頁: | 157 | 來源出版物: | Inflammation research : official journal of the European Histamine Research Society ... [et al.] | 摘要: | Psoriasis is an inflammatory disease characterized by skin thickening with silvery white desquamation due to dysregulated inflammatory pathways and elevated levels of inflammatory cytokines. Biologic agents targeting these inflammatory cytokines have brought about significant improvement in clearing psoriatic lesions in patients with moderate-to-severe psoriasis. Moreover, biologics exert both beneficial and detrimental effects on comorbidities in psoriasis, which include increased risk of cardiovascular events, metabolic syndrome, among other conditions. However, non-immune functions of cytokines targeted by biologics, and, hence, the potential risks and benefits of biologics for psoriasis to different organs/systems and comorbidities, have not been well elucidated. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/621250 | ISSN: | 1023-3830 | DOI: | 10.1007/s00011-021-01528-0 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。