https://scholars.lib.ntu.edu.tw/handle/123456789/621255
標題: | Trial of Spesolimab for Generalized Pustular Psoriasis | 作者: | Bachelez, Hervé Choon, Siew-Eng Marrakchi, Slaheddine Burden, A David TSEN-FANG TSAI Morita, Akimichi Navarini, Alexander A Zheng, Min et al., |
關鍵字: | JAPANESE PATIENTS; PLAQUE PSORIASIS; MUTATIONS; PROFILES; SYMPTOMS; EFFICACY; SAFETY | 公開日期: | 2021 | 出版社: | MASSACHUSETTS MEDICAL SOC | 卷: | 385 | 期: | 26 | 起(迄)頁: | 2431 | 來源出版物: | The New England journal of medicine | 摘要: | Generalized pustular psoriasis (GPP) is a rare, life-threatening, inflammatory skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 signaling is involved in the pathogenesis of this disorder. Spesolimab, a humanized anti-interleukin-36 receptor monoclonal antibody, is being studied for the treatment of GPP flares. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/621255 | ISSN: | 0028-4793 | DOI: | 10.1056/NEJMoa2111563 |
顯示於: | 醫學系 |
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