https://scholars.lib.ntu.edu.tw/handle/123456789/623770
標題: | Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Patients With Parkinson Disease | 作者: | Chen, Szu-Ju CHIEH-CHANG CHEN Liao, Hsin-Yu Lin, Ya-Ting Wu, Yu-Wei JYH-MING LIOU MING-SHIANG WU CHING-HUA KUO CHIN-HSIEN LIN |
關鍵字: | DIETARY HABITS; PATHOGENESIS; PROGRESSION; EXPRESSION; PATHWAYS; DEMENTIA; MODEL | 公開日期: | 22-二月-2022 | 出版社: | LIPPINCOTT WILLIAMS & WILKINS | 卷: | 98 | 期: | 8 | 起(迄)頁: | E848 | 來源出版物: | Neurology | 摘要: | Short-chain fatty acids (SCFAs) are gut microbial metabolites that promote the disease process in a rodent model of Parkinson disease (PD), but fecal levels of SCFAs in patients with PD are reduced. Simultaneous assessments of fecal and plasma SCFA levels, and their interrelationships with the PD disease process, are scarce. We aimed to compare fecal and plasma levels of different SCFA subtypes in patients with PD and healthy controls to delineate their interrelations and link to gut microbiota changes and clinical severity of PD. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/623770 | ISSN: | 0028-3878 | DOI: | 10.1212/WNL.0000000000013225 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。