https://scholars.lib.ntu.edu.tw/handle/123456789/624136
標題: | Temporal Dynamics of Anti-Type 1 Interferon Autoantibodies in Patients With Coronavirus Disease 2019 | 作者: | Shaw, Elana R Rosen, Lindsey B ARISTINE CHENG Dobbs, Kerry Delmonte, Ottavia M Ferré, Elise M N Schmitt, Monica M Imberti, Luisa Quaresima, Virginia Lionakis, Michail S Notarangelo, Luigi D Holland, Steven M Su, Helen C |
關鍵字: | COVID-19; IFN-α; IFN-ω; autoantibodies; convalescence | 公開日期: | 24-八月-2022 | 出版社: | OXFORD UNIV PRESS INC | 卷: | 75 | 期: | 1 | 起(迄)頁: | E1192 | 來源出版物: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 摘要: | Binding levels and neutralization activity of anti-type 1 interferon autoantibodies peaked during acute coronavirus disease 2019 and markedly decreased thereafter. Most patients maintained some ability to neutralize type 1 interferon into convalescence despite lower levels of binding immunoglobulin G. Identifying these autoantibodies in healthy individuals before the development of critical viral disease may be challenging. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/624136 | ISSN: | 1058-4838 | DOI: | 10.1093/cid/ciab1002 |
顯示於: | 醫學系 |
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