https://scholars.lib.ntu.edu.tw/handle/123456789/624526
標題: | Association between SLICC/ACR damage index and outcomes for lupus patients after cardiac valve surgery | 作者: | Hu, Szu-Yen CHIAO-FENG CHENG Yang, Kelvin Jeason CHIH-HSIEN WANG NAI-HSIN CHI RON-BIN HSU YIH-SHARNG CHEN HSI-YU YU |
關鍵字: | Cardiac valve prostheses; Cardiac valves; Follow-up study; Systemic lupus erythematosus | 公開日期: | 9-九月-2022 | 出版社: | OXFORD UNIV PRESS | 卷: | 35 | 期: | 4 | 起(迄)頁: | ivac221 | 來源出版物: | Interactive cardiovascular and thoracic surgery | 摘要: | Systemic lupus erythematosus (SLE) is associated with multi-organ damage including cardiac valve, which may need valvular operation. However, methods for outcome prediction and prosthetic valve selection are unclear in SLE patients undergoing cardiac valve surgery. Twenty-five SLE patients receiving valvular operation in a single institute between 2002 and 2020 were enrolled. Systemic Lupus International Collaborative Clinics/American College of Rheumatology Damage Index (SLICC/ACR damage index, SDI) was applied to evaluate the damage severity. Clinical outcomes were compared between patients with different SDI. The hospital survival rate was 88%, and long-term survival rate was 59.5% and 40.2% at 5 and 10 years. The median SDI was 4 (interquartile range 3-6) in our study, patients were then grouped into higher SDI (defined as SDI ≥ 5, n = 11) and lower SDI group (defined as SDI < 5, n = 14). The in-hospital survival rate (72.2% vs 100%, P = 0.074) and 5-year survival rate (18.2% vs 92.9%, P < 0.001) were lower in higher SDI group, compared to lower SDI group. SDI score was associated with long-term outcome for SLE patients receiving cardiac valve surgery. SDI ≥ 5 was associated with very poor long-term outcomes. This finding implicates that xenograft might be a reasonable choice for SLE patients with SDI ≥ 5. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/624526 | ISSN: | 1569-9293 | DOI: | 10.1093/icvts/ivac221 |
顯示於: | 醫學系 |
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