https://scholars.lib.ntu.edu.tw/handle/123456789/626806
標題: | Serum Vascular Adhesion Protein-1 Predicts End-Stage Renal Disease in Patients with Type 2 Diabetes | 作者: | HUNG-YUAN LI Lin, Hung-An FENG-JUNG NIEN VIN-CENT WU YI-DER JIANG TIEN-JYUN CHANG HSIEN-LI KAO MAO-SHIN LIN Wei, Jung-Nan Lin, Cheng-Hsin SHYANG-RONG SHIH CHI-SHENG HUNG LEE-MING CHUANG |
關鍵字: | SENSITIVE AMINE OXIDASE; CHRONIC KIDNEY-DISEASE; RISK-FACTORS; COMPLICATIONS; MORTALITY; INFLAMMATION; DIALYSIS; MARKERS; PEOPLE; TAIWAN | 公開日期: | 2016 | 出版社: | PUBLIC LIBRARY SCIENCE | 卷: | 11 | 期: | 2 | 來源出版物: | PloS one | 摘要: | Diabetes is the leading cause of end-stage renal disease (ESRD) worldwide. Vascular adhesion protein-1 (VAP-1) participates in inflammation and catalyzes the deamination of primary amines into aldehydes, hydrogen peroxide, and ammonia, both of which are involved in the pathogenesis of diabetic complications. We have shown that serum VAP-1 is higher in patients with diabetes and in patients with chronic kidney disease (CKD), and can predict cardiovascular mortality in subjects with diabetes. In this study, we investigated if serum VAP-1 can predict ESRD in diabetic subjects. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626806 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0147981 |
顯示於: | 醫學系 |
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