https://scholars.lib.ntu.edu.tw/handle/123456789/626932
標題: | Major adverse cardiovascular and limb events in people with diabetes treated with GLP-1 receptor agonists vs SGLT2 inhibitors | 作者: | Lin, Donna Shu-Han Yu, An-Li Lo, Hao-Yun Lien, Cheng-Wei JEN-KUANG LEE WEN-JONE CHEN |
關鍵字: | Amputation; Diabetes; Glucagon-like peptide-1 receptor agonists; Major adverse cardiac events; Major adverse limb events; Sodium–glucose cotransporter 2 inhibitors | 公開日期: | 十二月-2022 | 出版社: | SPRINGER | 卷: | 65 | 期: | 12 | 起(迄)頁: | 2032 | 來源出版物: | Diabetologia | 摘要: | This study aimed to assess the real-world outcomes of people with diabetes mellitus treated with glucagon-like peptide-1 receptor agonists (GLP1RAs) compared with those treated with sodium-glucose cotransporter 2 inhibitors (SGLT2is) in terms of major adverse cardiovascular and limb events. Peripheral artery disease is a common cause of morbidity in people with diabetes. Previous cardiovascular outcome trials have demonstrated the benefits of GLP1RAs and SGLT2is for reducing various cardiovascular events, but the safety and efficacy of these drugs on limb outcomes remain subject to debate and ambiguity. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626932 | ISSN: | 0012-186X | DOI: | 10.1007/s00125-022-05772-9 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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