https://scholars.lib.ntu.edu.tw/handle/123456789/627042
標題: | Impact of cooking oil fume exposure and fume extractor use on lung cancer risk in non-smoking Han Chinese women | 作者: | Chen, Tzu-Yu Fang, Yao-Hwei Chen, Hui-Ling Chang, Chin-Hao Huang, Hsin Chen, Yi-Song Liao, Kuo-Meng Wu, Hsiao-Yu Chang, Gee-Chen Tsai, Ying-Huang Wang, Chih-Liang Chen, Yuh-Min Huang, Ming-Shyan Su, Wu-Chou PAN-CHYR YANG Chen, Chien-Jen Hsiao, Chin-Fu Hsiung, Chao A |
關鍵字: | NEVER-SMOKING WOMEN; CIGARETTE-SMOKING; AIR-POLLUTION; FOLLOW-UP; GENOTOXICITY; POLYMORPHISM; ASSOCIATION; SMOKERS; COHORT; FUELS | 公開日期: | 21-四月-2020 | 出版社: | NATURE RESEARCH | 卷: | 10 | 期: | 1 | 來源出版物: | Scientific reports | 摘要: | Smoking tobacco is the major risk factor for developing lung cancer. However, most Han Chinese women with lung cancer are nonsmokers. Chinese cooking methods usually generate various carcinogens in fumes that may inevitably be inhaled by those who cook the food, most of whom are female. We investigated the associations of cooking habits and exposure to cooking fumes with lung cancer among non-smoking Han Chinese women. This study was conducted on 1,302 lung cancer cases and 1,302 matched healthy controls in Taiwan during 2002-2010. Two indices, "cooking time-years" and "fume extractor use ratio," were developed. The former was used to explore the relationship between cumulative exposure to cooking oil fumes and lung cancer; the latter was used to assess the impact of fume extractor use for different ratio-of-use groups. Using logistic models, we found a dose-response association between cooking fume exposure and lung cancer (odds ratios of 1, 1.63, 1.67, 2.14, and 3.17 across increasing levels of cooking time-years). However, long-term use of a fume extractor in cooking can reduce the risk of lung cancer by about 50%. Furthermore, we provide evidence that cooking habits, involving cooking methods and oil use, are associated with risk of lung cancer. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627042 | ISSN: | 2045-2322 | DOI: | 10.1038/s41598-020-63656-7 |
顯示於: | 醫學系 |
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