https://scholars.lib.ntu.edu.tw/handle/123456789/627219
標題: | Indoor Air Pollution Increases the Risk of Lung Cancer | 作者: | KE-CHENG CHEN SHIH-WEI TSAI Shie, Ruei-Hao Zeng, Chian HSIAO-YU YANG |
關鍵字: | bioaccumulation; combustion sources; exposure assessment; indoor air pollutants; machine learning; pleural fluid | 公開日期: | 21-一月-2022 | 出版社: | MDPI | 卷: | 19 | 期: | 3 | 來源出版物: | International Journal of Environmental Research and Public Health | 摘要: | (1) Background: Cooking and burning incense are important sources of indoor air pollutants. No studies have provided biological evidence of air pollutants in the lungs to support this association. Analysis of pleural fluid may be used to measure the internal exposure dose of air pollutants in the lung. The objective of this study was to provide biological evidence of indoor air pollutants and estimate their risk of lung cancer. (2) Methods: We analyzed 14 common air pollutants in the pleural fluid of 39 cases of lung adenocarcinoma and 40 nonmalignant controls by gas chromatography-mass spectrometry. (3) Results: When we excluded the current smokers and adjusted for age, the adjusted odds ratios (ORs) were 2.22 (95% confidence interval CI = 0.77-6.44) for habitual cooking at home and 3.05 (95% CI = 1.06-8.84) for indoor incense burning. In females, the adjusted ORs were 5.39 (95% CI = 1.11-26.20) for habitual cooking at home and 6.01 (95% CI = 1.14-31.66) for indoor incense burning. In pleural fluid, the most important exposure biomarkers for lung cancer were naphthalene, ethylbenzene, and o-xylene. (4) Conclusions: Habitual cooking and indoor incense burning increased the risk of lung adenocarcinoma. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627219 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123024552&doi=10.3390%2fijerph19031164&partnerID=40&md5=433a2cc0ed50933b4b2b090aa5855ddd |
ISSN: | 16617827 | DOI: | 10.3390/ijerph19031164 |
顯示於: | 環境與職業健康科學研究所 |
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